In the context of the deepening development of the digital economy, the traditional university-enterprise collaborative innovation and entrepreneurship education model in the field of higher education is facing structural contradictions such as inefficient resource integration, loose collaborative mechanisms, and the virtualization of practical teaching. This study reveals the enabling mechanism of digital technology on school-enterprise collaboration and proposes a four-dimensional implementation path of “curriculum system–practice platform–education reform–evaluation system.” Digital technology builds a two-way circulation mechanism of knowledge flow between schools and enterprises through the data middle platform, deepens collaborative education by relying on the virtual co-research platform, innovates the ability cultivation paradigm with technologies such as VR/AR, and constructs a dynamic evaluation system using all-dimensional data. Research shows that digital empowerment can break through the temporal and spatial barriers and information asymmetry of the traditional model, improve the efficiency of resource allocation between schools and enterprises, and increase the conversion rate of students’ practical projects. In the future, it is necessary to further expand the application of technology in the top-level design of talent cultivation, improve the cross-departmental policy coordination and ethical review mechanism, and provide theoretical and practical paradigms for cultivating high-quality compound talents with data thinking, innovation ability, and industry adaptability in the digital economy era.
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