The existence of the spiritual self is a prerequisite for the occurrence of social process. Without soul and self, human society cannot exist. However, if the mind and self are not produced in the social process, the individual organism cannot have the semiotic self. George Herbert Mead’s general method of macro social evolution is combined with some micro themes about biology and social psychology, which brings together many schools of thought, such as cognitive theory, structuralism, conflict theory, social change and system theory, as well as develops a philosophy of science and a comprehensive social theory.