Based on the IB curriculum concepts of “inquiry-based learning”, “interdisciplinary integration”, and “differentiated assessment”, this paper proposes differentiated teaching strategies centered on the cultivation of scientific thinking. By means of dynamic hierarchical grouping, contextualized case design, virtual simulation experiments, and a multi-evaluation system, a personalized learning path adapting to students with different cognitive levels is constructed. Research shows that this strategy can significantly improve students’ experimental design ability and critical thinking.
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