College should serve local economy closer, enterprise structure upgrading also improves requirements for personnel, so a collision and integration of college campus culture and corporate culture is accelerating. This paper starts from the relationship explication between the two cultures and the significance explication of their melange, in view of the problem of integration of this two culture, the paper propose five countermeasures: put the essence of enterprise culture into the "3-outlooks" and "3-styles" education, capture the key of two culture integration, establish the main line of integration, integrate college practice education resources, and promote undergraduate innovative and entrepreneurial ability.