This study proposes an innovative clinical practice competency cultivation system for infectious diseases—“Smart Platform + Practical Training Base + Layered Training”—which aims to comprehensively enhance students’ practical abilities in infectious disease prevention and control through the integration of modern information technologies, practical teaching resources, and layered training approaches. By optimizing teaching content to incorporate new diagnostic and therapeutic technologies, public health emergency response, and cutting-edge advancements, the system establishes three-tiered practical training (foundational, intermediate, and comprehensive levels) to holistically improve students’ clinical competencies. Effectiveness evaluations demonstrate that the system has been widely acknowledged by students, faculty, and public health practitioners as significantly enhancing students’ practical skills and professional competencies. The future prospects section outlines optimization plans, including the integration of advanced technologies, expansion of practical training bases, and strengthening of international collaboration, aiming to better align with future public health needs.
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