Ideological and political education in colleges and universities is a complex system, which needs to strengthen mutual cooperation among subsystems with the help of synergetic theory to make the internal state of system from disorder to order, from independence to relevance, so as to achieve the effect of cooperative education. In order to promote the in-depth combination of synergetic theory with ideological and political education in colleges and universities and to enhance synergy level, it is necessary to strengthen and improve the construction of synergetic education mechanism, and empower the construction of political and ideological synergetic education with a sound synergetic mechanism.