Keywords
Biomanufacturing
Cosmetic raw materials
Recombinant collagen
Cell factory
Green manufacturing
Submitted : 2026-01-14
Accepted : 2026-01-29
Published : 2026-02-13
Abstract
With the rapid development of synthetic biology technology, the cosmetics industry has entered an unprecedented technological revolution. Against this background, this paper conducts research from two aspects: on the one hand, by analyzing the popular application of synthetic biology technologies such as gene editing, microbial fermentation, and enzyme engineering, the paper summarizes the breakthrough progress of the cosmetics industry in recombinant humanized collagen, natural plant functional ingredients, and new emulsification and stabilization systems; on the other hand, by elaborating on the advantages of synthetic biology in safety, efficacy, and sustainability in cosmetic production and manufacturing, the paper further looks forward to the future mature application and multi-disciplinary integrated development path. The aim is to promote the cosmetics industry to accelerate towards personalization, precision, and sustainable development, and truly usher in a new era of biomanufacturing.
References
Sun X, 2024, Research Progress on Key Gene Screening and Engineering Design in the Production of Natural Products by Synthetic Biology. Biochemical Engineering, 10(6): 190–194 + 200.
Deng SY, Jin JM, Wu H, 2024, Research Progress on the Application of Ferulic Acid in Cosmetics. China Surfactant Detergent & Cosmetics, 54(12): 1489–1496.
Zuo YM, Zhang JJ, Lian JC, 2025, Application of Saccharomyces cerevisiae Enabling Technology in the Synthesis of Cosmetic Raw Materials. Synthetic Biology, 6(2): 233–253.
Wei LZ, Wang J, Sun XX, et al., 2025, Research on the Biosynthesis of Flavonoids and Their Application in Cosmetics. Synthetic Biology, 6(2): 373–390.
Yi JX, Tang YL, Li CY, et al., 2025, Research Progress on the Application and Biosynthesis of Amino Acid Derivatives in Cosmetics. Synthetic Biology, 6(2): 254–289.
Jia JL, 2024, Biology: Exploring the Sustainable Charm of Synthetic Biology. China Cosmetics, 2024(5): 58–59.
Wang YC, Xu RR, Wang XC, et al., 2024, Recombinant Humanized Collagen and Skincare Raw Materials. Shandong Chemical Industry, 53(12): 92–96.
Zhao M, Chi ZY, Lai DL, et al., 2024, Research Progress on Microbial Synthesis of Medical Aesthetic Active Ingredients. Chinese Journal of Biotechnology, 40(8): 2489–2512.
Li SY, Chen JL, 2024, Comparative Analysis of Cosmetic Raw Material Production Technologies. Chemical Enterprise Management, 2024(16): 83–86.
Liu L, 2024, Where Will the Future Development of Chinese Cosmetics Go (V) — Synthetic Biotechnology Chapter. China Cosmetics, 2024(2): 24–33.
Lin XF, 2023, Market Characteristics and Development Strategies of the Domestic Cosmetics Industry. Guangdong Chemical Industry, 50(20): 64–65 + 68.
Shi MY, Zhao W, Yang AQ, et al., 2024, Raw Material Preparation and Application of Phenolic Acids in Cosmetics. Fine Chemicals, 241(2): 245–256 + 276.
Wang HQ, Gao H, Xin FX, 2023, Analysis of the Development Trend of the Synthetic Biology Industry Under the Background of the 14th Five-Year Plan. Journal of Biology, 40(3): 1–5.
Guo XP, 2021, Synthetic Biology — The Innovation Driving Force of Cosmetic Raw Materials. China Cosmetics, 2021(12): 18–24.
Kang Z, 2017, Biosynthesis of Glycosaminoglycans and Their Oligosaccharides Based on Synthetic Biology. Proceedings of the 11th Academic Annual Conference of the Chinese Society of Biotechnology and the 2017 National Biotechnology Conference. Chinese Society of Biotechnology, Chinese Society of Biotechnology, 1.