Keywords
Type 2 diabetes mellitus
Evaluation methods
Lifestyle intervention
Submitted : 2024-12-08
Accepted : 2024-12-23
Published : 2025-01-07
Abstract
Prediabetes is a heterogeneous condition, encompassing various pathological phenotypes such as hyperinsulinemia, tissue-specific insulin resistance (IR), systemic IR, and β-cell dysfunction. A significant proportion of individuals with prediabetes remain undiagnosed. Furthermore, although lifestyle interventions have demonstrated efficacy in improving prediabetic conditions, some individuals with prediabetes progress to type 2 diabetes mellitus. This study aims to summarize effective evaluation methods for identifying distinct pathological phenotypes of prediabetes and targeted lifestyle intervention strategies to mitigate the progression from prediabetes to diabetes.
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