Objective: To study the effect of the upper limbs on dosage in Gamma Knife treatment. Methods: The design function of the Luna-260TM Gamma Knife Radiotherapy Planning System was utilized, using a body phantom to simulate conventional treatment sites. Twenty sampling points were set for irradiation locations. Using five different collimator sizes commonly used in body treatments, treatment plans were designed under conditions with and without upper limbs, and sampling point irradiation time comparison data was collected to calculate and analyze dose error rates. Results: Across the 20 sampling points, the dose error range was from -16.09% to 0 when comparing treatment plans without upper limbs to those executed with upper limbs present, and from 0 to 19.75% in the reverse comparison. With the same prescription dose, location, and collimator size, dose error increased as the irradiation site moved closer to the upper limbs and decreased as the distance increased. Conclusion: In Gamma Knife treatment, the dose error decreases as the irradiation site is further from the upper limbs and increases when closer. Consistency in upper limb positioning is essential during Gamma Knife localization, planning, and execution. Although small, the upper limbs can significantly impact dosage, requiring stringent quality control to ensure the precision of treatment doses, thus safeguarding the effectiveness and safety of patient treatments.
Iyengar P, Timmerman RD, 2012, Stereotactic Ablative Radiotherapy for Non-Small Cell Lung Cancer: Rationale and Outcomes. Journal of the National Comprehensive Cancer Network, 10(12): 1514–1520.
Wang J, Liu B, Liu W, 2020, Impact of Arm Position on Volumetric Modulated Arc Therapy for Thoracic Stereotactic Radiotherapy. Chinese and Western Medicine Combined Cardiovascular Diseases Electronic Journal, 8(20): 168 + 173.
Hu C, Huang W, Zhai H, et al., 2020, Analysis of Follow-up Evaluation Results of the Quality Control Detection Specification for X- and Gamma-ray Stereotactic Radiotherapy Systems (WS582-2017). Chinese Radiation Health, 29(2): 138–141.
Huang Z, Cao F, Wang J, et al., 2023, Analysis and Study of Quality Control Measures for Radiotherapy Equipment in Jiangxi Province. Chinese Medical Device Information, 29(5): 18–20 + 34.
Li J, Liu X, Wang G, et al., 2022, Dosimetric Impact of Arm Position on CyberKnife Radiotherapy in Patients with Spinal Tumors. Journal of Peking University (Health Sciences), 54(1): 182–186.
Jin Y, He S, 2020, Brief Discussion on YY0775-2010 Long-distance Radiotherapy Planning System Requirements for High-energy X (γ) Beam Dose Calculation Accuracy and Test Methods. Chinese Medical Device Information, 26(9): 16–17 + 22.
Li C, Lu J, Tao C, et al., 2017, Analysis of Intensity-Modulated Radiotherapy Plan Dose-Volume Histograms Based on Quartile Values. Chinese Journal of Radiological Medicine and Protection, 37(10): 742–746.
Xu Y, Li X, Sun K, 2012, Comparative Verification Study of Two Radiotherapy Planning Systems. Tuberculosis and Thoracic Tumor, 2012(2): 118–120.
Huang Z, Cao F, Wang J, et al., 2023, Analysis and Study of Quality Control Measures for Radiotherapy Equipment in Jiangxi Province. Chinese Medical Device Information, 29(5): 18–20 + 34.
Cheng Y, Liu D, Xu D, et al., 2018, Clinical Study on Focal Dose Rate in Gamma Knife Treatment of Primary Trigeminal Neuralgia. Chinese Journal of Minimally Invasive Neurosurgery, 23(11): 485–487.