Keywords
Surgery
Combined spinal and epidural anesthesia
Analgesic effect
TNF-?
CRP level
Submitted : 2024-02-23
Accepted : 2024-03-09
Published : 2024-03-24
Abstract
Objective: To observe the analgesic effect of combined spinal and epidural anesthesia on older patients undergoing hip fracture surgery. Method: One hundred and twenty elderly hip fracture surgery patients treated in our hospital from January 2021 to December 2022 were selected and randomly divided into two groups, with 60 cases in the experimental group and 60 in the control group. The experimental group was given combined spinal-epidural anesthesia intervention measures, while the control group was given epidural anesthesia intervention measures. The analgesic effect, tumor necrosis factor-alpha (TNF-α), C-reactive protein (CRP) levels, and other observation indicators were analyzed after anesthesia intervention. Result: After the intervention, the analgesic effect and the evaluation results of the subjects in the experimental group were better than those in the control group (P < 0.05); the obtained values of TNF-α and CRP levels in the experimental group were higher than those of the control group (P < 0.05). Conclusion: The combined spinal- epidural anesthesia intervention demonstrated positive outcomes. The analgesic effect of patients during surgery and their inflammatory factor levels improved, which makes this intervention worthy of clinical application and promotion.
References
Zhang Z, 2023, Application of Spinal Anesthesia Combined with Epidural Anesthesia in Surgery for Elderly Patients with Hip Fracture. Huaihai Medicine, 41(4): 394–396.
Wang X, Wen J, Wang C, 2022, Optimization of Anesthesia Strategies for Hip Fracture Surgery in Elderly Patients. Journal of Clinical and Pathology, 42(3): 708–714.
Liu J, Liu Z, Chen Y, et al., 2022, Comparison of the Effects of Two Anesthesia Methods for Hip Fracture Surgery in the Elderly. Journal of Clinical Orthopedics, 25(6): 826–828.
Zhu X, 2021, Analysis of the Analgesic Effect of Combined Spinal-Epidural Anesthesia During Surgery in Elderly Patients with Hip Fractures. Chinese Practical Medicine, 16(33): 73–75.
Ren X, 2021, Evaluation of the Effectiveness of Combined Spinal-Epidural Anesthesia in Elderly Patients with Hip Fracture. Chinese Disability Medicine, 29(22): 36–37.
Ma M, 2021, Safety Study of Combined Spinal-Epidural Anesthesia in Elderly Patients with Hip Fracture. Chinese Practical Medicine, 16(17): 108–110.
Li X, Zhang J, Zhu Q, et al., 2021, Safety of Combined Anesthesia in Elderly Patients with Hip Fracture. Heilongjiang Traditional Chinese Medicine, 50(2): 14–15.
Weng C, Fan H, 2020, Safety of combined spinal-epidural anesthesia for elderly patients with hip fracture. Medical Theory and Practice, 33(1): 90–91.
Yang Z, Wang K, Huang Z, et al., 2021, Clinical Study on the Relationship Between Pre-Operative Nottingham Score and Postoperative Complications in Elderly Patients with Hip Fracture [J]. Journal of Clinical and Experimental Medicine, 20(20): 2181–2185.
Lu X, 2020, Safety of Combined Spinal-Epidural Block Anesthesia in Elderly Patients with Hip Fracture. Medical Equipment, 33(17): 130–131.