Keywords
miRNA
circRNA
Fibrosis
Apoptosis
Inflammation
Submitted : 2023-10-28
Accepted : 2023-11-12
Published : 2023-11-27
Abstract
Diabetic nephropathy (DN) accounts for approximately 20–40% of diabetic patients. It is one of the most common microvascular complications of diabetes and an important cause of end-stage renal disease (ESRD). Renal biopsy histopathology is an important means for early clinical diagnosis of DN, but because it is an invasive examination, it is not easily accepted by patients due to risks such as bleeding, infection, and thrombosis. Therefore, finding new biomarkers for diagnosing DN is of great significance for early treatment and improving patient prognosis. MicroRNA (miRNA) is a type of highly conserved endogenous non-coding RNA. More and more studies have shown that miRNA is involved in the pathological process of DN and renal fibrosis. This article summarizes the relevant research on miRNA in DN.
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