Relationship Between Glomerular Filtration Rate and Sarcopenic Obesity in Patients with Chronic Kidney Disease and Osteoporosis
Download PDF

Keywords

Chronic kidney disease
Osteoporosis
Sarcopenia

DOI

10.26689/jcnr.v7i5.5031

Submitted : 2023-08-23
Accepted : 2023-09-07
Published : 2023-09-22

Abstract

Objective: To explore the relationship between osteoporosis and sarcopenic obesity in patients with chronic kidney disease. Methods: A total of 102 patients with chronic kidney disease from June 2021 to May 2023 were included in this study. Patients underwent medical history interviews, physical exams, bone mineral density, muscle mass, and renal function assessments, including glomerular filtration rate and serum creatinine levels. Results: The occurrence of sarcopenic obesity in patients with chronic kidney disease + osteoporosis was notably higher at 41.03%, compared to 19.04% in patients with chronic kidney disease alone (P < 0.05). Significant distinctions were observed in muscle mass, bone density, serum creatinine, and glomerular filtration rate between the two groups: chronic kidney disease osteoporosis + sarcopenic obesity and chronic kidney disease + sarcopenic obesity (P < 0.05). Conclusion: There is a certain relationship between osteoporosis and sarcopenic obesity in patients with chronic kidney disease. Therefore, it is necessary to consider both aspects during treatment, and strengthen prevention and treatment measures to improve the quality of life and prognosis of patients.

References

Yu M, Zhang Y, Hong F, et al., 2021, Relationship Between Osteoporosis and Sarcopenic Obesity in Patients with Chronic Kidney Disease. Trauma and Emergency Electronic Journal, 9(03): 165–170 + 186.

Wang J, Yu G, Li Z, et al., 2021, The Relationship Between 24 H Proteinuria Level and Blood and Bone Markers in Patients with Chronic Kidney Disease. Modern Practical Medicine, 33(06): 823–825.

Wang X, Tang R, Liu B, 2021, Research Progress on the Common Pathogenesis of Osteoporosis and Vascular Calcification in Patients with Chronic Kidney Disease. Chinese Journal of Practical Internal Medicine, 41(06): 554–557.

Zhang H, Wang J, Liu F, 2021, Research Progress on the Relationship Between Chronic Kidney Disease Flora Imbalance and Sarcopenia. Chinese Experimental Diagnostics, 25(05): 789–791.

Cai Z, Hu X, Chen L, et al., 2021, Cross-Sectional Investigation of Osteoporosis and Cardiovascular Calcification in Patients with Chronic Kidney Disease at Different Stages. Journal of Sichuan University (Medical Edition), 52(02): 334-339.

Yu M, Zhang H, Hong F, et al., 2020, Clinical Research on Bone Mineral Density Changes in Patients with Chronic Kidney Disease and Sarcopenia. Chinese Journal of Osteoporosis, 26(08): 1159–1162.

Zhao B, Mao Y, 2020, Pay Attention to Sarcopenia in Elderly Patients with Chronic Kidney Disease. West China Medicine, 35(07): 762–765.

Fang J, Jiang H, Li X, et al., 2020, Changes and Clinical Significance of Serum 25 (OH) D, IGF-1 and Osteoporosis Indicators in Patients with Chronic Kidney Disease. Difficult Diseases Magazine, 19(04): 344–348.

Zhou H, Ou S, Zeng G, et al., 2020, The Relationship Between Phalangeal Bone Density and Related Indicators in Maintenance Hemodialysis Patients. Medical Review, 26(06): 1228–1232.

Song L, Cai X, Ao Q, et al., 2020, The Impact of Frailty on Sarcopenia in Elderly Male Patients with Chronic Kidney Disease. Chinese Journal of Cardiovascular and Cerebrovascular Diseases for the Elderly, 22(03): 249–252.

Li X, 2020, Study on the Status and Influencing Factors of Sarcopenia in Elderly Patients with Peritoneal Dialysis, dissertation, Chengde Medical College.

Zhang B, Wu C, Gui P, et al., 2019, The Effect of Comprehensive Rehabilitation Training on Elderly Chronic Kidney Disease Complicated with Sarcopenia. Chinese Rehabilitation Theory and Practice, 25(12): 1463–1468.

Song Y, Wen A, Guo W, 2019, A Case of Acute Kidney Injury Caused by Hypercalcemia in a Patient with Chronic Kidney Disease During Osteoporosis Treatment. Chinese Drug Application and Monitoring, 16(05): 317–319.

Li Q, Guo A, Weng M, 2019, Research Progress of Uremic Sarcopenia. Chinese New Clinical Medicine, 12(06): 693–696.

Li X, Mei F, 2018, Research Status of Bone Mineral Density and Related Factors in Patients with Chronic Kidney Disease. World Latest Medical Information Abstracts, 18(76): 101–102.