Research Progress of Traditional Chinese Medicine in the Treatment of Premature Ovarian Failure
Download PDF

Keywords

Premature ovarian failure (POF)
Traditional Chinese medicine (TCM)

DOI

10.26689/jcnr.v6i2.3643

Submitted : 2022-02-21
Accepted : 2022-03-08
Published : 2022-03-23

Abstract

Premature ovarian failure refers to a disease in which women usually present with amenorrhea, infertility, decreased estrogen secretion, and increased gonadotropin before the age of 40. It seriously endangers women’s health, making them prone to various endocrine reproductive and even systemic disorders. Its pathogenesis remains unclear; however, it may be related to genetic, immune, enzyme deficiency, iatrogenic, cyclin, psychology, and other factors. Traditional Chinese medicine believes that its etiology is related to the kidney, liver, and spleen. It can be divided into kidney deficiency and liver depression syndrome, liver and kidney Yin deficiency syndrome, spleen and kidney Yang deficiency syndrome, and so on. Traditional Chinese medicine is mainly made up of oral Chinese medicine, acupuncture, and other therapies. Through literature research, this paper discusses the etiology, pathological mechanism, and treatment of premature ovarian failure in the field of traditional Chinese medicine.

References

Jankowska K, 2017, Premature Ovarian Failure. Menopause Review, 16(2): 51-56. DOI: 10.5114/pm.2017.68592

Melekoglu R, Ciftci O, Eraslan S, et al., Beneficial Effects of Curcumin and Capsaicin on Cyclophosphamide-Induced Premature Ovarian Failure in a Rat Model. J Ovarian Res, 11(1): 33. DOI: 10.1186/s13048-018-0409-9

Gaytan F, Garcia-Galiano D, Dorfman MD, et al., 2014, Kisspeptin Receptor Haplo-Insufficiency Causes Premature Ovarian Failure Despite Preserved Gonadotropin Secretion. Endocrinology, 155(8): 3088-3097. DOI: 10.1210/en.2014-1110

Dragojevic-Dikic S, Marisavljevic D, Mitrovic A, et al., 2010, An Immunological Insight into Premature Ovarian Failure (POF). Autoimmun Rev, 9(11): 771-774. DOI: 10.1016/j.autrev.2010.06.008

Che Y, Ma H, 2018, Research Progress of Traditional Chinese Medicine in Premature Ovarian Failure. Asia Pacific Traditional Medicine, 2018(11): 93-95.

Wang Y, Su J, Di X, et al., 2019, Research Progress of Premature Ovarian Failure. Medical Review, 2019(19): 3895-3899.

Wang Y, Zhang L, 2019, Advances in Traditional Chinese Medicine Research on Premature Ovarian Failure. Journal of Qiannan Medical College for Nationalities, 2019(2): 100-103.

Bai Y, Fang M, Wu X, 2014, Fang Minggong’s Experience of Acupuncture and Moxibustion in the Treatment of Premature Ovarian Failure. Clinical Journal of Traditional Chinese Medicine, 2014(7): 669-671.

Liu Y, Fu B, Xiao Q, 2018, Prevention and Treatment of Ovarian Reserve Dysfunction in Kidney Deficiency and Liver Depression Type Based on the Idea of “Prevention and Treatment of Diseases”. Lishizhen Medicine and Materia Medica Research, 2018(5): 1165-1167.

Yang P, Mian Y, Hui J, 2020, Basic and Clinical Research Progress of Acupuncture and Moxibustion in the Treatment of Premature Ovarian Failure in Recent 5 Years. Journal of Modern Integrated Traditional Chinese and Western Medicine, 2020(8): 901-905.

Chen G, Shi Y, 2014, Overview of Research on Etiology, Pathogenesis and TCM Treatment of Premature Ovarian Failure. Journal of Liaoning University of Traditional Chinese Medicine, 2014(12): 205-208.

Zhao S, Ma L, Wu J, et al., 2015, Clinical Observation on the Treatment of Premature Ovarian Failure by Harmonizing the Heart and Spleen in Traditional Chinese Medicine. Beijing Traditional Chinese Medicine, 34(5): 386-388.

Teng X, Li P, 2016, Observation on the Curative Effect of Jianpi Bushen Huoxue Recipe in the Treatment of Premature Ovarian Failure with Spleen and Kidney Yang Deficiency Syndrome. Chinese Journal of Integrated Traditional Chinese and Western Medicine, 36(01): 119-122.

Hu L, Liu H, Zeng L, et al., 2017, Effect of Bushen Huoxue Recipe on Granulosa Cell TGF in Mice with Premature Ovarian Failure- ?1, TGF- ? Effects of RII and Smad2/3 Expression. Chinese Patent Medicine, 39(9): 2282-2284.

Xu B, Li M, Xiong S, 2017, Effect of Bushen Tiaojing Ointment on Sex Hormone Level in Patients with Premature Ovarian Failure of Kidney Deficiency Type. Journal of Guangzhou University of Traditional Chinese Medicine, 34(02): 167-172.

Zhao X, Xie Y, Zheng H, 2019, Haobo Chen Effect of Bushen Tiaojing Ointment on Premature Ovarian Failure with Kidney Deficiency and Its Effect on Sex Hormone and Immune Function. Chinese Journal of Traditional Chinese Medicine, 37(01): 192-196.

Yang Y, Tian H, Luo S, et al., 2021, Network Pharmacological Study on the Mechanism of Zigui Yijing Decoction in the Treatment of Premature Ovarian Failure. Journal of Guangzhou University of Traditional Chinese Medicine, 38(11): 2485-2491.

Zhang J, Sun Y, Huang H, et al., 2018, Analysis of Acupoint Selection Law of Acupuncture and Moxibustion in the Treatment of Premature Ovarian Failure Based on Data Mining Technology. Journal of Shandong University of Traditional Chinese Medicine, 42(6): 479-483.

Wu S, Yan J, 2018, Clinical Observation of Zusanli and Guanyuanwen Acupuncture Combined with Ginger Separated Moxibustion at Badao Point in the Treatment of Premature Ovarian Failure. Chinese Acupuncture, 38(12): 1267-1271.

Yao M, Wang Q, Pan H, et al., 2019, Acupuncture Treatment of Premature Ovarian Failure and Its Effect on Cytokine TNF-A, IFN- ? Effect of Expression Level. Chinese Acupuncture and Moxibustion, 39(11): 1181-1184.

Wu J, Ning Y, Chen Y, et al., 2019, Clinical Observation on the Therapeutic Effect of Acupuncture for Regulating Menstruation and Promoting Pregnancy on Premature Ovarian Failure. Shi Zhen, Guo Yi Guo Yao, 30(6): 1422-1423.

Yu X, Zhu X, Hua S, 2019, Clinical Observation of Umbilical Acupuncture Combined with Mixed Yuan Moxibustion in the Treatment of Premature Ovarian Failure. Guangming Traditional Chinese Medicine, 34(13): 2035-2037.

Chen J, Tang G, Tang H, et al., 2019, Clinical Study on Bushen Shugan Traditional Chinese Medicine Combined with Acupoint Catgut Embedding in the Treatment of Premature Ovarian Failure. Journal of Traditional Chinese Medicine, 47(2): 112-115.