Research Progress in the Effect Evaluation of GLP1-1 Agonists
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Keywords

Diabetes
GLP-1 receptor agonist
Effect evaluation
Adverse reaction

DOI

10.26689/jcnr.v6i1.2876

Submitted : 2021-12-20
Accepted : 2022-01-04
Published : 2022-01-19

Abstract

Glucagon-like peptide-1 (GLP-1) promotes insulin secretion, inhibits glucagon secretion, and repairs pancreatic islet cell function to enhance islet cell proliferation and regeneration. Furthermore, it includes a mechanism for weight loss and angiocarpy protection. This study covers the comparison of GLP-1 agonists with DPP-4 inhibitors and GLT-2 inhibitors, the mechanism of GLP-1 agonists, and its research possibilities based on a summary of current clinical tests of GLP-1 receptor agonists.

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