Objective: To explore the effects of mindfulness-based stress reduction (MBSR) training combined with dexmedetomidine hydrochloride preemptive sedation on postoperative sleep quality in patients undergoing laparoscopic ovarian tumor resection. By comparing postoperative sleep quality, pain scores, anxiety scores, and adverse reactions among three groups of patients, the clinical efficacy of this combined treatment was evaluated. Methods: A total of 123 patients undergoing laparoscopic ovarian tumor resection in the hospital from January 2022 to December 2023 were included. Based on the interventions, patients were randomly divided into three groups: Group I received dexmedetomidine hydrochloride preemptive sedation, Group II received MBSR training, and Group III received a combination of MBSR training and dexmedetomidine hydrochloride preemptive sedation. Preoperative SAS anxiety scores, postoperative adverse reactions (nausea, vomiting, respiratory depression, skin itching, etc.), VAS pain scores, Ramsay sedation scores, AIS sleep scores, and postoperative SAS anxiety scores were recorded and analyzed. Results: The results showed that Group III demonstrated significantly better postoperative sleep quality (first-day postoperative AIS score: 7.975 ± 1.98), pain relief (first-day postoperative VAS score: 2.97 ± 0.85), and anxiety improvement (first-day postoperative SAS score: 40.46 ± 2.12) compared to Groups I and II (P < 0.05). Additionally, Group III exhibited a lower incidence of adverse reactions, particularly in terms of nausea, vomiting, and respiratory depression. Conclusion: MBSR training combined with dexmedetomidine hydrochloride preemptive sedation effectively reduces perioperative stress responses, improves postoperative sleep quality, alleviates pain, and relieves anxiety in patients undergoing laparoscopic ovarian tumor resection, with good safety and tolerability. This study provides a novel intervention strategy for the postoperative rehabilitation of patients undergoing laparoscopic surgery, meriting further clinical application.
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