Therapeutic Efficacy of Reduced Glutathione in Emergency Treatment of Organophosphorus Pesticide Poisoning and Its Impact on ALT, AST, CRP, and IL-6 Levels

Abstract

Objective: To analyze the efficacy of reduced glutathione (GSH) in the emergency treatment of patients with organophosphorus pesticide poisoning (AOPP). Methods: A total of 100 AOPP patients admitted to the emergency department between January 2022 and January 2024 were selected and randomly divided into two groups. The observation group (n = 50) received GSH combined with conventional treatment, while the reference group (n = 50) received conventional treatment alone. The overall treatment efficacy, serum indicators, and adverse reaction rates were compared. Results: The observation group exhibited a higher overall treatment efficacy compared to the reference group (P < 0.05). Post-treatment, serum indicator levels in the observation group were lower than those in the reference group, and the adverse reaction rate was also lower in the observation group (P < 0.05). Conclusion: GSH can improve the overall treatment efficacy in AOPP patients, protect liver function, reduce inflammatory responses in the body, and minimize post-treatment adverse effects, thus accelerating recovery and demonstrating significant therapeutic advantages.