Abstract
Objective: To investigate the effect of
prostate volume on robot-assisted radical prostatectomy.
Methods: Clinical data of 75 patients underwent RARP
in the Affiliated Hospital of Qingdao University were
retrospectively analyzed. The patients were divided
into 3 groups according to size of prostate. A total of
35 cases with prostate volume less than 30ml were
recorded as group 1, 27 cases with volume of 30 to
50 ml were recorded as group 2, and 13 cases with
volume greater than 50ml were recorded as group
3. Age, BMI, preoperative PSA, operation time,
intraoperative bleeding volume, postoperative drainage
volume, indwelling time of catheter, indwelling time of
drainage tube, total hospitalization time, pathological
stage, surgical margin, urine control and biochemical
recurrence were observed. Results: All operations
were performed under Da Vinci robot assistance, and
no patient was transferred to open surgery. There was
no significant difference in age, preoperative PSA,
BMI, operation time, intraoperative bleeding volume,
postoperative drainage volume, indwelling time of
catheter, total hospitalization time, pathological stage,
rate of positive surgical margin and recovery of urinary
continence between the groups. Indwelling time of
drainage tube was longer in group with larger prostate,
6.4 (±4.5) days in group 1, 6.3 (±2.9) days in group 2
and 7.1 (±2.5) days in group 3. Gleason score was lower
in group with larger prostate, with statistical difference.
Conclusion: Prostate volume had no significant effect
on urinary control, rate of positive surgical margin and
recurrence after RARP. Gleason score of pathological
tissue was lower and indwelling time of drainage tube
was longer in patients with larger prostate after RARP.
Operation time and intraoperative bleeding volume
of large prostate patients underwent RARP need to
be further studied. RARP has certain advantages for
patients with large prostate.