Objective: To summarize the evidence of tube feeding intolerance in critically ill children, aiming to provide evidence-based information for clinical nursing staff. Methods: Evidence search was done in Chinese and English databases to guide network and professional associations at home and abroad. The search time limit was from January 2014 to January 2024, nearly 10 years of relevant literature, mainly including guidelines, consensus, expert advice, best practice, evidence summary, system evaluation, and meta-analysis. Literature quality evaluation and evidence extraction were independently performed by two researchers. Results: This paper included 13 articles, including three guidelines, three systematic evaluations, three expert opinions, and four expert consensus. Twenty-six pieces of evidence were summarized from 10 aspects of feeding intolerance definition, team building, nutritional assessment, nutritional preparation, feeding protocol, feeding route, feeding management, pipeline management, gastric residual volume, and drug application. Conclusion: This paper summarized the evidence of tube feeding intolerance in critically ill children, which can provide evidence-based information for clinical practice. The abdominal signs should be closely observed when evaluating feeding intolerance, focusing on the prevention and reduction of feeding interruption.
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