Keywords
Neutrophil-to-lymphocyte ratio (NLR)
Red blood cell distribution width (RDW)
Acute exacerbation of chronic obstructive pulmonary disease (AECOPD)
Pulmonary embolism
Submitted : 2024-07-15
Accepted : 2024-07-30
Published : 2024-08-14
Abstract
Objective: To investigate the diagnostic value of the monocyte-to-large-platelet ratio (MLPR), neutrophil-to-lymphocyte ratio (NLR), and red blood cell distribution width (RDW) for pulmonary embolism (PE) in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods: A total of 60 elderly AECOPD patients were enrolled and divided into embolus group (12 cases) and thrombus group (48 cases) according to whether they were combined with pulmonary embolism and the MLPR, NLR, and RDW values of the two groups were determined respectively. Results: The patients in the two groups had different degrees of vascular structural and functional abnormalities, and the MLPR, NLR, and RDW in the embolus group were significantly higher than those in the thrombus group (P < 0.05); while the differences in NLR and RDW between the two groups were not significant. Conclusion: MLPR, NLR, and RDW can provide an objective basis for assessing PE in elderly AECOPD patients.
References
Chen Y, Li X, Yang Z, 2024, Research Progress of Anticoagulation Therapy for Acute Exacerbation of Chronic Obstructive Pulmonary Disease Combined with VTE. Chinese Journal of Lung Diseases (Electronic Edition), 17(2): 316–319.
Liu L, Li M, Wan R, 2024, Diagnostic Value of Laboratory Indexes in Patients with Pulmonary Tuberculosis Combined with Pulmonary Embolism. Clinical Meta-Analysis, 39(2): 134–139.
Zhang W, Gao Y, Cheng S, 2024, Observation on the Effect of Adding and Subtracting Tong Yang Xuan Paralysis Tang on the Prognosis of Patients with Advanced Lung Cancer Combined with (Qi Stagnation and Blood Stasis Type) Acute Non-Massive Pulmonary Embolism. Sichuan Traditional Chinese Medicine, 42(2): 100–103.
Lu W, Liu G, Qiao H, 2024, Study on the Relationship Between Lower Extremity Deep Vein Thrombus Density, Serum cTnI and Hcy Levels and the Risk of Combined Pulmonary Embolism in Patients with Deep Vein Thrombosis. Journal of Clinical and Experimental Medicine, 23(3): 309–312.
Chen X, Meilang Q, 2024, Comparison of the Effectiveness and Safety of Different Doses of Low Molecular Heparin Sodium Anticoagulation for the Treatment of Patients with Cerebral Hemorrhage Combined with Pulmonary Embolism. Clinical Rational Drug Use, 17(4): 70–73.
Jiao X, Gong J, Kuang T, et al., 2024, Prevalence and Clinical Characterization of Pulmonary Embolism Combined with Acute Exacerbation of Chronic Obstructive Pulmonary Disease. Advances in Cardiovascular Disease, 45(1): 84–90.
Pan Y, Lu L, Lin R, et al., 2024, Effect of Low Molecular Weight Heparin Calcium Combined with Rivaroxaban in the Treatment of Patients with Lung Cancer Combined with Acute Pulmonary Embolism. Chinese and Foreign Medical Treatment, 43(1): 12–16.
Wang W, Liu S, Liu Q, et al., 2024, A Retrospective Study of Clinical Characteristics of Patients with Acute Pulmonary Embolism Combined with Thrombocytopenia. Chinese General Medicine, 27(27): 3372–3377.
Jiang J, Wang J, Xie A, et al., 2023, Combined Pulmonary Embolism in Elderly Patients with Chronic Obstructive Pulmonary Disease and Its Influencing Factors. China Health Engineering, 22(5): 649–651.
Yang G, Mi Y, Xiao Y, et al., 2023, Analysis of Long-Term Prognosis and Associated Factors in Patients with Acute Pulmonary Embolism Combined with Malignant Tumor. Journal of Cardiopulmonary Vascular Disease, 42(9): 916–921.