Clinical Observation on the Treatment of Pre and Postmenopausal Syndromes by Modified Wumei Decoction

Abstract

Objective: To compare the efficacy of Wumei Decoction in pre and postmenopausal patients and its effect on follicle-stimulating hormone (FSH) and estradiol (E2). Methods: Sixty-four patients who attended the Department of Traditional Chinese Medicine I in Cangzhou City Central Hospital from January 2020 to January 2022 were selected and randomly divided into treatment group and control group, 32 cases in each group. The treatment group took modified Wumei Decoction orally, 1 dose of water boiled 2 times a day, divided into 2 warm doses; the control group took Livial orally, 2.5 mg/times, 1 time/day, and the observation cycles were all for 3 months. Kupperman score, FSH, E2, clinical symptoms and clinical efficacy were compared between the two groups before and after treatment. Results: The Kupperman score of the two groups decreased after treatment, and the difference was statistically significant; the total effective rate of the treatment group was higher than that of the control group, and the difference was statistically significant; there was no statistical significance in the comparison of FSH before and after the treatment of the two groups, but the FSH values of the two groups were significantly lower than those before, and the difference was statistically significant; there was no statistically significant difference in the comparison of E2 of the two groups before treatment, and the E2 values of the two groups were higher than those of the control group after the treatment. After the treatment, E2 of the two groups of patients was significantly higher than before, and the difference was statistically significant. After treatment, E2 of the treatment group was higher than that of the control group, and the comparison between the groups was statistically significant. Conclusion: There was no significant difference between modified Wumei Decoction and Livial in lowering follicle-stimulating hormone levels; modified Wumei Decoction was superior in raising oestradiol; and modified Wumei Decoction was relatively effective in improving clinical symptoms.