A Review of Abiraterone Acetate for the Treatment of Metastatic Castration-Resistant Prostate Cancer
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Keywords

Abiraterone acetate
Prostate cancer
Indications
Treatment program

DOI

10.26689/jcnr.v8i6.7627

Submitted : 2024-06-18
Accepted : 2024-07-03
Published : 2024-07-18

Abstract

Prostate cancer is a common malignant tumor of the urinary system in men, and the incidence and detection rate of prostate cancer have been rising significantly in recent years. Androgens play an important role in the occurrence and development of prostate cancer, so hormone deprivation therapy has become an essential means of prostate cancer treatment. Abiraterone acetate is a therapeutic agent for prostate cancer by inhibiting the enzyme activity of CYP17, thereby blocking androgen biosynthesis. In this paper, we present a review of the current mechanism of action of abiraterone acetate for prostate cancer treatment, research progress, and its side effects and limitations. It is expected to provide help for further research on the treatment of prostate cancer.

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