Objective: To assess the management effect of comprehensive nursing management on blood donation services in blood stations. Methods: Sixty-four individuals who donated blood at a blood station between September 2021 and September 2023 were selected and randomly assigned into two groups of 32 each. The first group received comprehensive nursing management, while the second group received routine nursing management. Blood donation indexes and observational indexes such as adverse reactions were compared between the groups. Results: The total blood donation volume and qualified blood donation volume were higher in the first group than in the second group. The amount of discarded blood and the rate of blood discards were lower in the first group compared to the second group (P < 0.05). Additionally, the adverse reaction rate in the first group was lower, the blood donation comfort scores were higher, the psychological state scores were lower, and the quality of care scores were higher than those in the second group (P < 0.05). Conclusion: Comprehensive nursing management can improve the efficiency of blood donation, reduce the rate of blood discards, decrease the incidence of adverse reactions, alleviate negative psychological states of blood donors, and enhance both the comfort level of blood donation and the quality of care provided.
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