Keywords
Low-dose Betaloc
Amiodarone
Submitted : 2023-08-23
Accepted : 2023-09-07
Published : 2023-09-22
Abstract
Objective: To explore and analyze the clinical effect of small and medium doses of Betaloc combined with
amiodarone in the treatment of ventricular arrhythmia. Methods: 60 patients with ventricular arrhythmia that were treated in the Department of Cardiology of our hospital from May 2018–May 2023 were selected for this study, and they were divided into a research group (n = 30) and a reference group (n = 30). The study group was treated with small doses of Betaloc and amiodarone, while the reference group was treated with conventional treatment. The total efficacy of medication, QRS interval, standard deviation of normal-to-normal (NN) intervals (SDNN), root mean square of successive differences between normal heartbeats (RMSSD), standard deviation of the average NN intervals (SDANN), and incidence of adverse reactions were compared between the groups. Results: The effectiveness of medication in the study group was significantly higher than that in the reference group (P < 0.05). Besides, there was no statistically significant difference (P > 0.05) in the QRS interval and SDNN between the two groups before treatment. After treatment, the QRS interval and SDNN of the study group were significantly lower than those of the reference group (P < 0.05). Before treatment, there was no significant difference in RMSSD and SDANN between groups (P > 0.05). After treatment, RMSSD and SDANN in the study group were significantly better than those in the reference group (P < 0.05), and the difference was statistically
significant. The incidence of adverse reactions in the study group was significantly lower than that in the reference group (P < 0.05), and the difference was statistically significant. Conclusion: Small doses of Betoprolol and amiodarone is more effective in the treatment of ventricular arrhythmia, which has the value of popularization and application.
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