The Role and Safety of Personalized Care in Improving Thrombocytopenia after Lymphoma Chemotherapy
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Keywords

Individualized care
Lymphoma chemotherapy
Thrombocytopenia
Safety
Effect

DOI

10.26689/jcnr.v7i5.5231

Submitted : 2023-08-23
Accepted : 2023-09-07
Published : 2023-09-22

Abstract

Objective: To explore and analyze the effect and safety of personalized nursing in improving thrombocytopenia
after lymphoma chemotherapy. Methods: 80 lymphoma patients with thrombocytopenia after lymphoma chemotherapy in the Department of Hematology of our hospital from May 2021 to May 2023 were selected as the research objects, and they were divided into an experimental group and reference group by random drawing, with 40 cases in each group. The experimental group received individualized nursing, and the reference group received routine nursing. The platelet count, platelet-related indicators, incidence of adverse reactions, and life scores were compared between the two groups. Results: Before the intervention, there was no significant difference in platelet count between the groups (P > 0.05); after the intervention, the platelet count in the experimental group was significantly higher compared to the reference group (P < 0.05). In the experimental group, the duration for platelet decline and the time for platelets to normalize were notably
shorter compared to the reference group (P < 0.05). Moreover, the personality group displayed a significantly lower incidence of adverse reactions than the reference group (P < 0.05). Prior to the intervention, there were no statistically significant differences (P > 0.05) in the life scores between the two groups, such as functional condition, symptom manifestation, and health scores among the groups. However, post-intervention, the personality group exhibited a significant improvement in those scores compared to the reference group (P < 0.05). Conclusion: Individualized nursing can optimize the platelet level in thrombocytopenia after lymphoma chemotherapy, improve symptoms, and reduce the occurrence of adverse reactions.

References

Zhai P, Zhai W, Huang Y, et al., 2023, Construction of TCM Quality of Life Scale for Children with Chronic Immune Thrombocytopenia Based on Delphi Method. Journal of Tianjin University of Traditional Chinese Medicine, 42(03): 317–321.

Zhao H, Wang W, 2023, Nursing Research on the Treatment of Immune Thrombocytopenic Purpura with Traditional Chinese Medicine Yuzu Prescription (Xiaodianling) Combined with Syndrome Differentiation and Nursing of Traditional Chinese Medicine. Sichuan Traditional Chinese Medicine, 41(05): 212–215.

Wang H, Ma X, 2022, Effect of Nursing Risk Management on Thromboelastographic Parameters and Prognosis of High-Dose Methylprednisolone Treatment of Children with Idiopathic Thrombocytopenic Purpura. Thrombosis and Hemostasis, 28(01): 152–154.

Gao Y, 2021, Study on the Effect of Whole-Course Nursing Intervention on the Effect and Compliance of Hormone Therapy in Children with Immune Thrombocytopenic Purpura. Contemporary Clinical Medicine, 34(05): 54-55 + 41.

Wang C, 2021, The Clinical Efficacy of Comprehensive Nursing Intervention Combined with Jianpi Huoxue Decoction on Thrombocytopenia and the Influence of Serological Indicators in Patients. Practical Chinese Medicine Journal, 35(10): 83–86.

Yu Y, Zhang X, Lin G, et al., 2021, The Impact of Comprehensive Intervention on The Clinical Effect and Quality of Life of Patients with Immune Thrombocytopenia Drug Therapy. Chinese Medicine Herald, 18(07): 185–188.

Zhang L, 2020, Effect of Nursing Measures on Thrombocytopenia After Intra-Aortic Balloon Pump Implantation in Patients with Acute Myocardial Infarction. Chinese Journal of Metallurgical Industry Medicine, 37(05): 602.

Xiang F, 2020, The Effect of Nursing Intervention on the Clinical Efficacy and Safety of High-Dose Methylprednisolone in the Treatment of Children with Idiopathic Thrombocytopenic Purpura. Journal of Clinical Rational Drug Use, 13(26): 123–124.

Lian R, Feng X, Li G, et al., 2020, Research on the Effect of Full-Course Seamless Nursing on the Compliance of Hormone Therapy in Children with Idiopathic Thrombocytopenic Purpura. Medical Diet Therapy and Health, 18(15): 155 + 157.

Fan L, 2020, Nursing Effect Observation of High-Dose Gamma Globulin Combined with Glucocorticoids on Idiopathic Thrombocytopenic Purpura. Electronic Journal of Cardiovascular Diseases of Integrated Traditional Chinese and Western Medicine, 8(08): 162–163.

Guo Y, 2020, Study on the Effect of Evidence-Based Nursing on Quality of Life and Sleep in Patients with Thrombotic Thrombocytopenic Purpura Treated with Plasma Exchange. Chinese and Foreign Medicine, 39(01): 135–137.

Gong H, Wang Z, 2019, The Effect of Recombinant Human Thrombopoietin in the Treatment of Thrombocytopenia During Pregnancy and its Influence on Interleukin and Interferon. Chinese Journal of Family Planning, 27(12): 1652–1655.

Wang G, Ma H, Zhao J, 2019, Observation on the Effect of Recombinant Human Thrombopoietin Therapy for Thrombocytopenia after Chemotherapy in Acute Leukemia. Electronic Journal of Clinical Medicine Literature, 6(82): 52.

Guo J, Liu L, Zhang L, et al., 2019, Application of Cluster Nursing in a Case of Acute Myeloid Leukemia Relapsed After Microtransplantation and Allogeneic Hematopoietic Stem Cell Transplantation. Chinese Medicine and Clinic, 19(14): 2464–2465.

Zhang Y, Shen X, 2019, Observation on the Preventive Effect of Empathic Nursing on Postoperative Complications of Laparoscopic Surgery in Patients with Refractory Thrombocytopenic Purpura. Wisdom Health, 5(12): 109–110.