Keywords
; Pelvic inflammatory disease (damp-heat stasis type)
Treatment effect
Inflammatory factor
Fibrinogen
Plasma viscosity
Submitted : 2022-10-22
Accepted : 2022-11-06
Published : 2022-11-21
Abstract
Objective: This study was undertaken to evaluate the clinical efficacy of Western medicine combined with Chinese medicine for pelvic inflammatory disease (damp-heat and stasis type). Methods: Seventy-four patients who were diagnosed with pelvic inflammatory disease (damp-heat and stasis type) by our hospital during July 2021 to July 2022 were randomized into two groups: the participants in the control group received conventional Western medicine treatment, and the participants in the study group received Western medicine combined with Chinese medicine. Results: After treatment, the total effectiveness of the control group (72.98%) was significantly lower than that of the study group (94.59%), (P < 0.05); the whole blood viscosity high cut, whole blood viscosity low cut, fibrinogen and plasma viscosity of the control group were all lower than those of the study group (P < 0.05); the levels of CRP, IL-6, and TNF-? in the control group were higher and IL-2 levels in the control group were lower than those in the study group (P < 0.05). Conclusion: Western medicine combined with Chinese medicine is more effective in curing damp-heat and stasis-type pelvic inflammatory disease by improving the blood rheological indexes and lowering the level of inflammatory factors.
References
Li C, Huo Y, Liu X, et al., 2020, Study on the Efficacy of Yin Qiao Hong Jao Tang on Secondary Infertility in Chronic Pelvic Inflammatory Disease Caused by Damp-Heat and Stagnation. Journal of Changchun University of Traditional Chinese Medicine, 36(3): 529–532.
Liu Y, Liu Z, Zhou D, et al., 2020, A Randomized, Double-Blind, Double-Model, Positive Drug-Parallel Controlled, Multi-center Clinical Study of Jinying Capsule in the Treatment of Pelvic Inflammatory Disease (Damp-Heat-Embedded Evidence). Chinese Journal of Practical Gynecology and Obstetrics, 36(2): 163–167.
Hu CHF, Jian H, Chen J, et al., 2020, Clinical Observation on the Treatment of the Sequelae of Pelvic Inflammatory Diseases with Damp-Heat and Stagnation Evidence by Combining the Internal Administration of Qing-Heat and Blood-regulating Tang with Wu-Wei Disinfecting Drink Enema. Chinese Journal of Experimental Formulary, 26(20): 111–116.
Lu Y, Lou J, Feng X, et al., 2021, Efficacy and Safety of Gynostemma Capsule Combined with Antibacterial Drugs in the Treatment of Pelvic Inflammatory Diseases: A Randomized Controlled Clinical Study. Chinese Journal of Obstetrics and Gynecology, 22(4): 383–385.
Li LL, Xu ZZ, Zhang AJ, et al., 2022, Clinical Efficacy of Combined Enema with Electromagnetic Wave for Chronic Pelvic Inflammatory Disease. Chinese Patent Medicine, 44(6): 1810–1814.
Wang X, Feng C, Gulinur Z, et al., 2020, Clinical Effect Analysis of Combined Chinese and Western Medicine in the Treatment of Giant Pelvic Abscess in Women. Chinese Maternal and Child Health Care, 35(8):1404-1407.
Wang Y, Cai M, Wei S, et al., 2020, Experience of Mr. Wang Jojiu, a Famous Gynecologist of Sichuan School, in Treating the Sequelae of Pelvic Inflammatory Diseases. Sichuan Traditional Chinese Medicine, 38(3): 50–52.
Stewart LM, Stewart C, Spilsbury K, et al., 2020, Association Between Pelvic Inflammatory Disease, Infertility, Ectopic Pregnancy and the Development of Ovarian Serous Borderline Tumor, Mucinous Borderline Tumor and Low-Grade Serous Carcinoma. Gynecologic Oncology, 156(3): 611–615.
Gao ZY, Liu SH, Li XJ, et al., 2020, Effects of Combined Chinese and Western Medicine Therapy on Inflammatory Factors and Blood Rheology in Patients with Chronic Pelvic Inflammatory Disease. Sichuan Traditional Chinese Medicine, 38(3): 179–182.
Blaikie L, Kay G, Lin P, 2020, Synthesis and In Vitro Evaluation of Vanillin Derivatives as Multi-Target Therapeutics for the Treatment of Alzheimer’s disease. Bioorganic & Medicinal Chemistry Letters, 30(21):127505.
Xu X, Zong CH, Liu J, et al., 2020, Study on the Distribution of Symptoms and Medication Pattern of Chronic Pelvic Pain in the Treatment of Pelvic Inflammatory Disease Sequelae in Chinese Medicine Based on Data Mining. World Journal of Integrated Chinese and Western Medicine, 15(12): 2166–2172.
Yang Y, Chi TV, Zeng S, et al., 2020, Tracking Evidences of Coptis Chinensis for the Treatment of Inflammatory Bowel Disease from Pharmacological, Pharmacokinetic to Clinical Studies. Journal of Ethnopharmacology, 268(6): 113573.
Shao M, Qu Q, Yan H, 2021, Efficacy of Gui Zhi Fu Ling Wan Combined with Hexi Jiao Zemeran Huang Wan Plus Reduction in the Treatment of cold and Stasis Type Pelvic Inflammatory Masses. Journal of Modern Traditional Chinese and Western Medicine, 30(11): 1225–1228.
Zhang S, Zhang L, Long K, et al., 2020, Evaluation of Clinical Efficacy of Integrated Traditional Chinese and Western Medicine in the Treatment of Acute Respiratory Distress Syndrome. Medicine, 99(25): e20341.
Liu Y, Zeng S, Li Y, et al., 2020, The Effect of Acupoint Application of Traditional Chinese Medicine for the Treatment of Chronic Obstructive Pulmonary Disease: A Protocol for Systematic Review and Meta-Analysis. Medicine, 99(43): e22730.