Keywords
Test tube baby
Newborn of natural delivery
Perinatal stage
Complication
Submitted : 2022-06-27
Accepted : 2022-07-12
Published : 2022-07-27
Abstract
This study was conducted to compare the perinatal complications for newborns by In vitro fertilization with embryo transfer (IVF-ET) and natural delivery. Respectively 50 cases of the IVF-ET and 50 cases of the natural delivery were selected from Hospital of Chengde Medical University as research subjects. All the recruited cases were selected with the newborns from April, 2021 to April, 2022. Defining the IVF-ET as the test group, while the natural delivery as the control group to compare and analyze the perinatal situations and the incidences of complications in both the groups. This study showed that the incidences of pregnancy-induced hypertension, diabetes, multiple pregnancy, premature delivery, and cesarean section in the test group were significantly (p<0.05) higher, than the control group. In addition, the incidences of neonatal respiratory distress syndrome (NRDS) and hyperbilirubinemia of newborns in the test group were statistical (p<0.05) higher, compared to the control group. In contrast, there are no statistically significant differences in terms of hypoglycemia, pneumonia, and neonatal asphyxia incidences between the two groups (p>0.05). Interestingly, there is a significant difference (p<0.05) in the incidences of neonatal cardiac anomalies in both groups, however, no significant differences (p>0.05) were observed in terms of birth defects including hypospadias, the cleft lip and palate, polydactyly, anal atresia, and esophageal atresia in both the groups. In summary, the test tube babies of IVF-ET are more susceptible to complications in their perinatal stage compared with natural delivery newborns, therefore, during the clinical development physicians should strengthen clinical attention and take proactive healthcare management, in order to maintain the health and life of the newborns.
References
Yan X, 2020, Comparison on the Perinatal Outcomes Between Test Tube Babies with IVF-ET and Natural Delivery Newborns. Modern Doctor, 58(7): 66–68.
Zhong L, 2020, Clinical Characteristics and Perinatal Outcomes Related Factors of Placental Implantation, and Construction and Optimization of Prognostic Prediction Models: A Large Cohort Study. Southern Medical University, Guangdong.
Zhang H, Xiao H, Yi H et al., 2020, The Relationship Among Sleep Quality, Pregnant Stress, and Psychological Resilience of the Pregnancy with IVF-ET[J]. Chinese Mental Health Journal, 34(10): 817–821.
Chen H, 2020, The Follow-Up Study on the Neuropsychiatric Development of Offspring with IVF-ET, 17(9): 82–84.
Zhang Y, Li X, Chen L, 2020, The treatment Effect of Baotaiyin to the Threatened Abortion After IVF-ET. Jilin Journal of Traditional Chinese Medicine, 40(3): 361–363.
Tan H, 2020, Study on the Comprehensive Healthcare Patterns of Patients with Polycystic Ovarian Syndrome Performed IVF-ET. Diet Health Journal, 7(15): 113.
Wang H, 2020, The Effect of Early Pregnancy Bleeding on Pregnancy Outcomes After IVF-ET. Jilin University, Jilin.
Chen C, Zhao X, 2020, Analysis on the Clinical Characteristics of Patients with Early Eclampsia After IVF-ET. Chinese Journal of Obstetric Emergency (Electronic Edition), 9(2): 106–110.
Mi W, 2020, The Management and Nursing Experience on Intramuscular Injection of Progesterone After IVF-ET. Journal of Medical Aesthetics and Cosmetology, 29(12): 112.
Wang L, Zhao J, Liu F et al., 2020, The Analysis on the Reason of Abnormal Fertilization During IVF-ET. Disease Surveillance and Control, 14(3): 237–243.
Wang H, Li Y, Ren H et al., 2019, The Comparison and Analysis on Maternal and Infant Outcomes of Twins Between by IVF-ET and Natural Pregnancy. Chinese Journal of Medicine Guide, 17(8): 145–146.
Lu J, Tang X, Gu Y, 2019, The Analysis on the Clinical Outcomes of Twins by IVF-ET or Natural Pregnancy. Modern Practical Medicine, 31(1): 77–79.
Li Y, 2019, The Clinical Comparison and Analysis on Twins by IVF-ET or Natural Pregnancy. The Journal of Clinical Medical Literature, 6(93): 39.
Liu Q, 2019, The Comparison and Analysis on the Clinical Outcomes of Twin Pregnancy Between by IVF-ET and Natural Pregnancy. Electronic Journal of Practical Gynecologic Endocrinology, 6(25): 75 + 82.
Liu F, 2019, The Study on the Effect Factors of Live Birth of Multiple Pregnancy with ART. Nanjing Medical University, Jiangsu.
Huang L, Li L, Zhang Z, 2020, The Comparison on the Perinatal Complications and Neonatal Birth Outcomes Between Fresh Embryo Transferring and Natural Pregnancy in Single Pregnancy. Journal of Reproductive Medicine, 29(12): 1655–1658.
Sun H, Yu C, Gao Y, 2020, The Comparison on the Perinatal Complications and Neonatal Situations After Frozen Embryo Transferring Between in Artificial Cycle and Natural Cycle. Modern Medical Journal, 48(11): 1367–1371.
Nie H, 2020, The Effect of Planed Delivery on the Outcomes of Vaginal Birth Rate, Birth Process, and Delivery. China Medicine and Pharmacy, 10(6): 94–96 + 142.
Pang Y, 2020, The Analysis on Perinatal Outcomes of Single Pregnancy After ART. Shanxi Medical University, Shanxi.
Xu X, 2020, The Effect of the Birth Weight of Full-Term Infant to the Perinatal Outcomes of Maternal and Infant. Guangzhou Medical University.
Wang H, Gu Y, Lu J et al., 2020, The Analysis on Fertility Status, Complications, and Pregnant Adverse Outcomes in 310 Cases of Elder Puerperae. Chinese Journal of General Practice, 18(4): 609–611.
Yan J, 2020, Discussion for Clinical Outcomes of Singletons with Vanishing Twin Syndrome Following In Vitro Fertilization-Double Embryo Transfer. Zhengzhou University, Henan.
Ko E, Fndk RB, Akkaya H, et al., 2021, Comparison of Hematological Parameters and Perinatal Outcomes Between COVID-19 Pregnancies and Healthy Pregnancy Cohort. Journal of Perinatal Medicine, 49(2): 141–147.
Gunay T, Turgut A, Bor ED, et al., 2020, Comparison of Maternal and Fetal Complications in Pregnant Women with Breech Presentation Undergoing Spontaneous or Induced Vaginal Delivery, or Cesarean Delivery. Taiwanese Journal of Obstetrics and Gynecology, 59(3): 392–397.
Erta S, Erin S, Dundar O, et al., 2020, Anogenital Distance in Newborn Infants Conceived by Assisted Reproduction and Natural Conception. Reproductive Biomedicine Online, 41(3): 474–482.