Keywords
Hyperbaric oxygen therapy
Different pressures
Clinical efficacy
Submitted : 2022-04-30
Accepted : 2022-05-15
Published : 2022-05-30
Abstract
Objective: To observe the efficacy and significance of hyperbaric oxygen at different pressures in the treatment of diffuse axonal injury (DAI). Methods: Sixty patients with DAI were randomly divided into 1.8 ATA group (30 cases) and 2.2 ATA group (30 cases). The routine treatment for each group was the same. The 1.8 ATA group received hyperbaric oxygen therapy under 1.8 ATA on the basis of routine treatment, whereas the 2.2 ATA group received hyperbaric oxygen therapy under 2.2 ATA on the basis of routine treatment. The therapy was given once a day over 3 consecutive courses, with each course having 10 sessions. The Glasgow Coma Scale (GCS) on day 10, day 20, and day 30 after treatment, as well as the Glasgow Outcome Scale (GOS) after 6 months were compared between the two groups. Results: The mean GCS on day 10, day 20, and day 30 after treatment, as well as the mean GOS after 6 months of treatment in the 2.2 ATA group were significantly higher than those in the 1.8 ATA group (p < 0.05). Conclusion: For patients with diffuse axonal injury, hyperbaric oxygen therapy is more effective with 2.2 ATA compared with 1.8 ATA.
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