Premature ovarian failure refers to a disease in which women usually present with amenorrhea, infertility, decreased estrogen secretion, and increased gonadotropin before the age of 40. It seriously endangers women’s health, making them prone to various endocrine reproductive and even systemic disorders. Its pathogenesis remains unclear; however, it may be related to genetic, immune, enzyme deficiency, iatrogenic, cyclin, psychology, and other factors. Traditional Chinese medicine believes that its etiology is related to the kidney, liver, and spleen. It can be divided into kidney deficiency and liver depression syndrome, liver and kidney Yin deficiency syndrome, spleen and kidney Yang deficiency syndrome, and so on. Traditional Chinese medicine is mainly made up of oral Chinese medicine, acupuncture, and other therapies. Through literature research, this paper discusses the etiology, pathological mechanism, and treatment of premature ovarian failure in the field of traditional Chinese medicine.
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