Keywords
Single nostril transsphenoidal resection of pituitary adenoma
Pituitary adenoma
Submitted : 2021-12-25
Accepted : 2022-01-09
Published : 2022-01-24
Abstract
Objective: This study mainly discusses the clinical effect of treating pituitary adenoma by using single nostril transsphenoidal resection of pituitary adenoma under neuro-endoscope, and analyzes the influence on hospitalization time and bleeding volume. Methods: A total of 335 patients with pituitary adenoma treated in our hospital from January 2017 to January 2019 were randomly selected for study. The patients were divided into two groups by number table method. 167 patients in the reference group underwent single nostril transsphenoidal resection of pituitary adenoma under microscope. Also, 168 patients in the study group underwent single nostril transsphenoidal resection of pituitary adenoma under neuroendoscope. The hospitalization time and bleeding volume and other surgical treatment effects were observed and compared. Results: There was no significant difference in the levels of prolactin (PRL), adrenocorticotropic hormone (ACTH) and thyroid stimulating hormone (TSH) between the two groups before operation (P > 0.05); After surgical treatment, the levels of PRL, ACTH and TSH in the study group were lower than those in the control group (P < 0.05); In terms of surgical indexes, the operation time and hospital stay in the study group were shorter than those in the reference group, and the amount of surgical bleeding was less than that in the reference group (P < 0.05); The total tumor resection rate in the study group was higher than that in the reference group, and the incidence of complications such as nasal septal defect, cerebrospinal fluid leakage and diabetes insipidus in the study group was lower than that in the reference group (P < 0.05). Conclusion: For pituitary adenoma diseases, using single nostril transsphenoidal resection of pituitary adenoma under neuroendoscope can improve the tumor resection rate, reduce the bleeding volume and shorten postoperative hospitalization time.
References
Dong W, Yue C, Zhang Y, et al., 2020, Effect of Treating Different Level of Pituitary Adenoma by Using Endonasal Transsphenoidal Surgery under Neuroendoscope and Analysis of Measures to Reduce Postoperative Complication. Clinical Medicine of China, 036(002): 166-170.
Qu Z, Tian J, Hu Y, et al., 2019, Effect of Single Nostril Transsphenoidal Resection of Pituitary Adenoma under Neuroendoscope on Serum IGF-1 Level in Patients with Pituitary Tumor after Operation. Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease, 17(18): 132-134.
Cui Y, Cheng P, Liu Y, et al., 2019, Comparison of Therapeutic Effects of Neuroendoscopic Intracapsular Resection and External Separation in the Treatment of Pituitary Adenomas. Chinese Journal of Clinical Neurosurgery, 24(12): 43-45.
Xu X, Yang Z, Song J, et al., 2020, Therapeutic Effect of Treating Recurrent Nonfunctional Pituitary Adenoma by Using Endonasal Transsphenoidal Surgery under Neuroendoscope and Microscope. Chinese Journal of Contemporary Neurology and Neurosurgery, 20(03): 68-73.
Guo H, 2019, Effect Evaluation of Treating Pituitary Adenoma by Transsphenoidal Endoscopic Pituitary Tumor Resection on Stress Level and Pituitary Function. Woman's Day, 000(021): 43.
Chen R, Liu Y, 2019, Effect Comparison of Resection of Pituitary Adenoma under Microscope and Single Nostril Transsphenoidal Resection of Pituitary Adenoma under Neuroendoscope. Chinese Journal of Practical Medicine, 2019, 046 (022): 75-78.
Yue X, Mo F, Pan B, 2020, Risk Factors and Management of Common Complications after Endonosal Transsphenoidal Resection of Pituitary Adenoma under Neuroendoscope. Journal of Hebei Medical University, 41(04): 121-124.
Chen J, Huo Y, Shan G, et al., 2019, Comparison of Therapeutic Effect of Endonasal Transsphenoidal Neuroendoscopic Surgery and Microscopic Surgery for Pituitary Adenoma. Zhejiang Journal of Traumatic Surgery, 024(005): 984-985.