Keywords
Type II respiratory failure
Non-invasive positive pressure ventilation
Failure mode and effects analysis
Nursing intervention
Quality of life
Submitted : 2026-04-20
Accepted : 2026-05-05
Published : 2026-05-20
Abstract
Objective: To investigate the application effect of nursing intervention based on Failure Mode and Effects Analysis (FMEA) in Non-Invasive Positive Pressure Ventilation (NPPV) treatment for patients with Chronic Obstructive Pulmonary Disease (COPD) complicated by Type II respiratory failure. Methods: Eighty patients with COPD complicated by Type II respiratory failure admitted from January 2024 to December 2025 were selected and randomly divided into a control group receiving conventional nursing and a study group receiving FMEA-based nursing intervention, with 40 cases in each group. Blood gas indicators, the incidence of adverse events, and quality of life scores were compared between the two groups after intervention. Results: After intervention, the blood gas indicators in the study group [PaO2 (69.58 ± 5.21) mmHg, PaCO2 (46.83 ± 4.56) mmHg, SaO2 (93.87 ± 2.75) %] were significantly better than those in the control group [PaO2 (63.12 ± 5.07) mmHg, PaCO2 (52.15 ± 4.89) mmHg, SaO2 (90.36 ± 2.89) %] (p < 0.05). The incidence of adverse events in the study group was significantly lower than that in the control group (p < 0.05). After intervention, the scores of all dimensions of the St. George’s Respiratory Questionnaire (SGRQ) in the study group were significantly lower than those in the control group (p < 0.05), indicating a more significant improvement in quality of life. Conclusion: The FMEA-based nursing intervention constructed in this study can effectively improve blood gas indicators during NPPV treatment for patients with COPD complicated by Type II respiratory failure, reduce the incidence of adverse events, and significantly improve patients’ quality of life, providing a widely applicable prospective risk prevention and control plan for specialized nursing management in clinical NPPV treatment.
References
Hu H, Hao L, Kang J, 2025, Construction and Validation of a Nomogram Prediction Model for the Prognosis and Outcome of Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease Complicated by Type II Respiratory Failure. Hainan Medical Journal, 36(13): 1844–1849.
Ding P, Li Q, 2025, Construction and Evaluation of a Prediction Model for the Outcome of Non-invasive Ventilation Treatment in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease Complicated by Type II Respiratory Failure. Anhui Medical and Pharmaceutical Journal, 29(11): 2271–2276.
Li Y, Chang Q, Chen F, et al., 2024, Observation on the Therapeutic Effect of ST Ventilation Mode of Non-invasive Ventilator Combined with Acetylcysteine Aerosol Inhalation in the Treatment of Chronic Obstructive Pulmonary Disease Complicated by Type II Respiratory Failure. Journal of Practical Hospital Clinical, 21(4): 115–118.
Wei S, Wang X, Wang J, et al., 2025, Analysis of the Application Effect of FMEA in Reducing the Rate of Tube Dislodgement in Patients in the Post Anesthesia Care Unit (PACU). Journal of Chongqing Medical University, 50(10): 1442–1447.
Chronic Obstructive Pulmonary Disease Group, Respiratory Diseases Branch, Chinese Medical Association, Chronic Obstructive Pulmonary Disease Working Committee, Respiratory Physicians Branch, Chinese Medical Doctor Association, 2021, Guidelines for the Diagnosis and Treatment of Chronic Obstructive Pulmonary Disease (Revised Edition 2021). Chinese Journal of Tuberculosis and Respiratory Diseases, 44(3): 170–205.
Nie W, Zheng C, Ding J, et al., 2024, Clinical Observation on the Treatment of Chronic Obstructive Pulmonary Disease Complicated by Respiratory Failure with Nashenjiangfei Pingchuan Decoction Combined with Non-invasive Ventilator. Journal of Emergency in Traditional Chinese Medicine, 33(9): 1640–1643.
Chen Y, 2024, Observation on the Effect of Providing Humanized Nursing Care to Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease Using Non-invasive Ventilators. Chinese Journal of Antituberculosis, 46(S02): 334–336.
Han H, Zhang L, Sun W, 2025, The Application Value of Failure Mode and Effect Analysis in Airway Humidification Management for Patients with Non-mechanical Ventilation Tracheal Intubation. Modern Journal of Integrated Traditional Chinese and Western Medicine, 34(10): 1444–1448.
Wang X, Chen G, Shang Y, 2025, The Application Effect of BiPAP Non-invasive Ventilator in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease Complicated by Type II Respiratory Failure. Medical Clinical Research, 42(5): 737–739.
Liu L, Zheng X, Wang R, et al., 2024, Analysis of the Preventive Effect of Process-oriented Nursing Intervention Based on Failure Mode and Effect Analysis on Medical Device-related Pressure Injuries in the Head and Face. China Medical Equipment, 21(4): 164–169.