This study examined a case of ventilator-associated pneumonia caused by Ralstonia mannitolilytica in a neonatal department in order to determine the source of infection and mode of transmission. Symptoms of infection began to appear on day 16 of admission, and both sputum and catheter tip cultures revealed R. mannitolilytica. The infection control department of the hospital later sampled and identified R. mannitolilytica in the ventilator tube that was used by the patient with the exact gene sequence as the infecting strain. These findings indicate that ventilator tubing is a significant contamination source of this pathogen, and hospitals need to enhance their disinfection methods of ventilator-related devices.
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