Evaluation Value of Cardiac Color Doppler Echocardiography in Assessing Poor Prognosis in Patients with Coronary Atherosclerotic Heart Disease
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Keywords

Coronary atherosclerotic heart disease
Color doppler echocardiography
Poor prognosis
Major adverse cardiovascular events
Ventricular function

DOI

10.26689/jcnr.v9i12.13471

Submitted : 2025-12-16
Accepted : 2025-12-31
Published : 2026-01-15

Abstract

Objective: To investigate the evaluation value of cardiac color Doppler echocardiography (CDE) in assessing poor prognosis in patients with coronary atherosclerotic heart disease (CAD). Methods: A retrospective review was conducted of 106 patients with coronary artery disease (CAD) who were treated in the hospital’s cardiovascular department between January 2023 and June 2024. All participants received baseline comprehensive Doppler echocardiography (CDE) assessments. Based on whether they experienced a Major Adverse Cardiovascular Event (MACE) within one year of follow-up, the patients were categorized into either a MACE group or a non-MACE group. The study compared baseline clinical information and CDE parameters, specifically left ventricular ejection fraction (LVEF), wall motion score index (WMSI), and mitral annular E/e’ ratio, between the two groups. Independent predictors of MACE were identified using multivariate logistic regression analysis. Results: A total of 29 out of the 106 patients experienced MACE during the one-year follow-up. Compared with the non-MACE group, the MACE group had a higher prevalence of diabetes mellitus. In terms of CDE parameters, the MACE group had a lower LVEF than the non-MACE group (p < 0.05), while WMSI, average E/e’, pulmonary artery systolic pressure (PASP), and mitral regurgitation (MR) proportion were all higher in the MACE group than in the non-MACE group (p < 0.05). Multifactor logistic regression analysis revealed that after adjusting for confounding factors such as diabetes, WMSI (OR = 3.003, 95% CI: 1.226–7.356, p = 0.016) and mean E/e’ (OR = 1.281, 95% CI: 1.006–1.539, p = 0.008) were independent predictors of the occurrence of major adverse cardiovascular events (MACE). Conclusion: WMSI and E/e’ diagnosed by color Doppler echocardiography (CDE) hold significant and independent assessment value for predicting poor prognosis in patients with coronary artery disease (CAD).

References

Hao G, Dong Y, Zhang B, et al., 2024, Trends in the Incidence of Ischemic Stroke Among Middle-Aged Populations Worldwide From 1990 to 2021 and Analysis Using the Age-Period-Cohort Model. Chinese Journal of Neurosurgical Disease Research, 18(6): 8–14.

Jiang P, Song Y, Xu J, et al., 2020, The Value of the Combination of Mean Platelet Volume and Platelet Volume Distribution Width in Predicting the Long-Term Prognosis of Stable Coronary Artery Disease. Chinese Circulation Journal, 35(3): 239–245.

Tang Y, Zhao L, Liu A, 2023, Research Progress in the Examination of Acute Coronary Syndrome Based on CCTA-Related Technologies. Chinese Journal of CT and MRI, 21(2): 178–179 + 187.

Ma X, Zhang Y, 2023, New Advances in CT Myocardial Perfusion Imaging. Radiologic Practice, 38(12): 1628–1633.

Ren J, 2023, Research Progress in Premature Coronary Heart Disease Complicated with Type 2 Diabetes Mellitus. Advances in Clinical Medicine, 13(9): 14043–14048.

Tang H, Tan J, 2024, A New Ultrasound Method for Assessing Left Ventricular Systolic Function: Myocardial Work. Medical Journal of West China, 36(4): 469–472.

Zhang S, Meng J, Zhou Y, et al., 2024, Prognostic Significance of Left Ventricular Ejection Fraction Reserve Obtained via Gated Myocardial Perfusion SPECT in Patients with Coronary Artery Disease and Reduced Stress Left Ventricular Ejection Fraction. Frontiers in Cardiovascular Medicine, 11: 1480501.

Han M, Zhao W, Wang X, et al., 2021, Echocardiographic Parameters as Predictors of Short- and Long-Term Adverse Cardiovascular Events in Patients with Acute Myocardial Infarction. International Journal of General Medicine, 14: 2297–2303.

Luo T, Tian W, Sun Q, et al., 2025, Prognosis Prediction in Patients with Non-ST-Segment Elevation Acute Coronary Syndrome Based on Echocardiographic Parameters: A Retrospective Cohort Study. Journal of Clinical Emergency, 26(3): 196–202.

Cai J, Liang Z, Feng W, et al., 2023, Correlation Between Left Atrial Strain and Left Ventricular Diastolic Function in Hypertensive Patients. Journal of Central South University (Medical Science), 48(6): 846–851.

Park J, Song Y, Kim S, et al., 2022, Long-Term Prognostic Value of E/e’ in Patients With ST-Segment Elevation Myocardial Infarction. Indian Heart Journal, 74(5): 369–374.