Analysis of the Efficacy of Shexiang Tongxin Dropping Pills Combined with Rosuvastatin Calcium and Clopidogrel Bisulfate Tablets in the Treatment of Phlegm-Heat and Blood Stasis Type Angina Pectoris of Coronary Heart Disease
Abstract
Objective: To investigate the clinical efficacy of Shexiang Tongxin Dropping Pills combined with rosuvastatin calcium and clopidogrel bisulfate tablets in treating phlegm-heat and blood stasis type angina pectoris of coronary heart disease. Methods: Sixty-four patients with phlegm-heat and blood stasis type angina pectoris of coronary heart disease, hospitalized at Lin’an District Hospital of Traditional Chinese Medicine from January 2024 to April 2025, were selected and randomly divided into a control group (administered 10mg of rosuvastatin calcium and 75mg of clopidogrel bisulfate once daily) and an observation group (administered 2 Shexiang Tongxin Dropping Pills three times daily in addition to the control group’s treatment regimen), with 32 patients in each group. The therapeutic effects of the two groups were compared. Results: After 56 days of treatment, the angina pectoris score in the observation group was significantly lower than that in the control group (4.49 ± 0.39 vs 4.88 ± 0.47, p < 0.05); the Seattle Angina Questionnaire (SAQ) score indicated improvement in the frequency of angina pectoris attacks. (SAQ-AF: 71.35 ± 5.29 vs. 64.25 ± 7.55, p < 0.05) and treatment satisfaction (SAQ-TS: 58.79 ± 6.22 vs. 54.16 ± 5.02, p < 0.05) were more significantly improved in the observation group. The total effective rate (96.87% vs. 90.62%, p < 0.05) and marked effective rate (62.50% vs. 31.25%) were higher in the observation group than in the control group. The Traditional Chinese Medicine (TCM) syndrome score (4.49 ± 0.39 vs. 4.88 ± 0.47, p < 0.05) and lipid index (LDL-C: 1.79 ± 0.31 vs. 1.99 ± 0.33 mmol/L, p < 0.05) decreased more significantly in the observation group. Conclusion: Shexiang Tongxin Dropping Pills combined with rosuvastatin calcium and clopidogrel bisulfate tablets demonstrated good efficacy and high safety in the treatment of phlegm-heat and blood stasis type angina pectoris associated with coronary heart disease.
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