Objective: To systematically explore the effectiveness of combining Enhanced Recovery After Surgery (ERAS) nursing and empathy intervention for postoperative patients with glioma. Methods: A total of 54 patients with glioma undergoing surgical treatment were selected for the study. The patients were admitted to the hospital between April 2023 and April 2025. The patients were divided into an observation group (n=27) and a control group (n=27) based on a random number table method. Relevant intervention indicators were compared between the two groups. Results: Compared with the control group, the postoperative recovery indicators in the observation group showed significant differences (P < 0.05). After intervention, the scores of stress psychological indicators, FMA, NHISS, and ADL in the observation group were all better than those in the control group (P < 0.05). The incidence of complications in the observation group was significantly lower than that in the control group (P < 0.05). Conclusion: The combined application of empathy intervention and ERAS nursing effectively regulates the postoperative stress psychological state of patients with glioma, significantly improves their limb and neurological functions as well as daily living abilities, accelerates postoperative recovery, and reduces complications. This approach is feasible for wider implementation.
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