Objective: To explore the key points of holistic nursing for children with membranous nephropathy (MN) combined with cerebral venous thrombosis, providing a reference for similar cases. Methods: The course of illness data of an 8-year-old boy with MN in the recurrent phase complicated with cerebral venous sinus thrombosis (CVST) was retroactively analyzed. Systematic nursing was implemented based on evidence-based practices, including strict neurological monitoring, anticoagulation and thrombolysis medication nursing, fluid and electrolyte management, hypoalbuminemia and edema nursing, complication prevention, and mental health education. Results: After 16 days of continuous infusion of low molecular weight heparin and supportive treatment, the child’s symptoms, such as headache and vomiting, disappeared. The reexamination of MRV showed significant absorption of thrombosis, and there was no residual neurological deficit. During the 3-month follow-up, the anticoagulation compliance was good, and there was no recurrence. Conclusion: Early identification of hypercoagulability risk, strengthening dynamic evaluation of neurological signs and coagulation indicators, standardizing anticoagulation and thrombolysis nursing, and cooperating with continuous health management can significantly improve the prognosis of children with MN combined with CVST.
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