Type III acute acquired comitant esotropia (AACE) is a special type of binocular coordination disorder with sudden onset characteristics, but its pathogenesis and treatment strategies remain unclear. This article analyzes the incidence and classification characteristics of Type III AACE, and explores its pathogenesis from multiple perspectives including clinical medicine, neuroscience, and neuro-ophthalmology. It is found that this disease is associated with factors such as decompensation of phoria, dysfunction of the visual center, abnormalities in the physiological and anatomical structure of extraocular muscles, accommodative factors, and disorders of convergence and divergence. The prognosis of Type III AACE is excellent with treatments such as botulinum toxin injection and surgery, and adjunctive therapies like prism adaptation test and visual function training can enhance the management effect. This article provides an in-depth analysis of the pathogenesis and cutting-edge treatment techniques for patients with Type III AACE, which can offer guidance for the subsequent diagnosis and treatment of such patients.
Shen J, Hua C, Lou H, et al., 2022, Changes in the Proportion of Hospitalizations for Acute Comitant Esotropia and Intermittent Exotropia Before and After the COVID-19 Epidemic. Ophthalmology, 31(6): 454–457.
Burian HM, Miller JE, 1958, Comitant Convergent Strabismus with Acute Onset. Am J Ophthalmol, 45(4 Pt 2): 55–64.
Rutstein RP, Lee SD, Zimmerman DR, 2017, Atypical Presentation of Acute Acquired Comitant Esotropia. Clin Exp Optom, 100(2): 192–194.
Wang X, Xie Q, Lu H, et al., 2015, Functional Magnetic Resonance Study on Cortical Activation Intensity in Patients with Comitant Strabismus. Recent Advances in Ophthalmology, 35(3): 258–262.
Huang X, Meng Y, Hu X, et al., 2022, The Effect of Different Treatment Methods on Acute Acquired Comitant Esotropia. Comput Math Methods Med, 2022: 5001594.
Zheng W, Zhang J, Chen J, et al. 2022, Independent Risk Factors of Type II Acute Acquired Concomitant Esotropia: A Matched Case-Control Study. Indian J Ophthalmol, 70(9): 3382.
Zhang G, Zhang L, Zhao R, et al., 2023, Efficacy Analysis of Botulinum Toxin Type A Injection and Extraocular Muscle Transposition for Patients with Acute Comitant Esotropia at Different Stages. Recent Advances in Ophthalmology, 43(4): 303–307.
Cui Q, Wang Z, Ma H, 2021, Short-Term Observation of the Effect of Botulinum Toxin Microinjection in the Treatment of Acute Comitant Esotropia. Ningxia Medical Journal, 43(4): 370–372.
Shi M, Zhou Y, Qin A, et al., 2021, Treatment of Acute Acquired Comitant Esotropia. BMC Ophthalmol, 21(1): 9.
Zhou S, Jin H, Li L, et al., 2017, Efficacy Analysis of Prism Adaptation Test Combined with Bilateral Lateral Rectus Muscle Recession in the Treatment of Basic Intermittent Exotropia. Jiangxi Medical Journal, 52(10): 969–971.
Qiang J, Huang J, Liu M, et al., 2024, Comparison of the Efficacy of Unilateral Medial Rectus Muscle Recession and Bilateral Medial Rectus Muscle Recession in the Treatment of Acute Comitant Esotropia in Adolescents. Chinese Journal of Aesthetic Medicine, 33(3): 29–32.
Xu X, Fu X, Lu L, 2022, Modified Parks Incision Combined with Rectus Muscle Linear Plication for the Treatment of Adult Comitant Strabismus. International Eye Science, 22(10): 1712–1716.
Chao X, 2020, Binocular Visual Analysis After Rectus Muscle Marginal Incision for the Correction of Comitant Esotropia. Capital Food and Medicine, 27(10): 16–16.
Wu X, Li Z, Gao M, 2024, Case Analysis of the Treatment of Acute Comitant Esotropia Using Full Refractive Correction and Visual Function Training. Glass, Enamel & Spectacles, 52(1): 14–16.