Objective: To explore the correlation between disease uncertainty and psychological distress in hospitalized patients with primary liver cancer, providing a basis for clinical nursing interventions. Methods: A convenient sampling method was used to select 82 patients with primary liver cancer from a tertiary first-class hospital in Guangzhou from September 2023 to March 2024 as the research subjects. General information questionnaires, the Mishel Uncertainty in Illness Scale-Adult Version (MUIS-A), and the Kessler Psychological Distress Scale (K10) were used for investigation. Pearson correlation analysis and linear regression analysis were performed to explore the relationship between the two. Results: The total score of disease uncertainty in hospitalized patients with primary liver cancer was (99.20 ± 8.79), and the total score of psychological distress was (22.87 ± 9.46), both at a medium level. There was a positive correlation between disease uncertainty and psychological distress (r = 0.360, P < 0.01), and the ambiguity dimension had the strongest correlation with psychological distress (r = 0.399, P < 0.01). Regression analysis showed that the ambiguity dimension had a significant predictive effect on psychological distress (β = 0.399, P < 0.01). Conclusion: There is a close correlation between disease uncertainty and psychological distress in patients with primary liver cancer. In clinical nursing, it is necessary to pay special attention to patients’ ambiguity regarding disease symptoms and prognosis. Targeted health education should be carried out to reduce their uncertainty, thereby improving their psychological state.
Fan SS, Yang LP, Zhao RN, et al., 2022, Comparative Analysis of the 2022 Edition of the Chinese Guidelines for the Diagnosis and Treatment of Primary Liver Cancer and the 2019 Edition of the Diagnosis and Treatment Specifications. Chinese Journal of Cancer Prevention and Treatment, 29(22): 1575–1578.
Su LY, Xing YR, 2022, Research on the Relationship Between Psychological Resilience, Personality, and Self-Efficacy in Patients with Primary Liver Cancer. Chinese General Practice Nursing, 20(24): 3434–3437.
Mishel MH, 1988, Uncertainty in Illness. Image: The Journal of Nursing Scholarship, 20(4): 225–232.
Kessler RC, Barker PR, Colpe LJ, et al., 2003, Screening for Serious Mental Illness in the General Population. Archives of General Psychiatry, 60(2): 184–189.
Xu QX, Li HY, Zhou YH, 2021, Analysis of the Current Status of Disease Uncertainty and Its Influencing Factors in Patients with Primary Liver Cancer. Cancer Progress, 19(04): 426–429.
Han J, Liu JE, Meng J, et al., 2008, Analysis of the Degree of Psychological Distress and Related Causes in Cancer Patients. Chinese Journal of Nursing, 43(06): 516–518.
Zhao FJ, Wang Q, Ren YH, et al., 2019, Changes in Serum CRP and hs-CRP Levels in Liver Cancer Patients with Depression and Their Impact on Prognosis. Journal of Practical Oncology, 33(01): 27–33.
Wan LJ, Xie GJ, Feng YY, et al., 2023, Current Status and Influencing Factors of Experiential Avoidance in Liver Cancer Patients. Nursing Practice and Research, 20(22): 3328–3333.