Transcatheter Hepatic Artery Embolization Versus Hepatic Artery Perfusion Chemoembolization in the Interventional Treatment of Primary Hepatocellular Carcinoma: Clinical Effect Observation
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Keywords

Catheter
Hepatic artery embolization
Hepatic artery perfusion chemoembolization
Primary liver cancer
Clinical effect

DOI

10.26689/ijgpn.v2i2.7369

Submitted : 2024-06-09
Accepted : 2024-06-24
Published : 2024-07-09

Abstract

Objective: To investigate the clinical effect of transcatheter hepatic artery embolization and hepatic artery perfusion chemoembolization on the interventional treatment of primary liver cancer. Methods: Eighty-two primary hepatocellular carcinoma patients who came to the outpatient clinic for treatment from August 2020 to November 2023 were selected as the study subjects. Based on the retrospective analysis, they were divided into 45 cases in the embolization group and 37 cases in the chemoembolization group according to the difference of treatment methods. The embolization group was treated with transcatheter hepatic artery embolization, and the chemoembolization group was treated with hepatic artery perfusion chemoembolization. The clinical efficacy, survival rate, survival quality score, serum tumor markers, and incidence of adverse reactions were observed in the two groups. Results: The clinical efficacy, survival quality score, and serum tumor markers of the chemoembolization group were higher than that of the embolization group, and the incidence of adverse reactions was lower than that of the embolization group, with statistically significant differences (P < 0.05). The survival rate of the chemoembolization group was not statistically significant when compared with that of the embolization group (P > 0.05). Conclusion: In the treatment of primary hepatocellular carcinoma, hepatic artery perfusion chemoembolization is better than transcatheter hepatic artery embolization, which can effectively improve the quality of patients’ survival and reduce the incidence of adverse reactions, and it is worth further popularized in the clinic.

References

Bian XS, Wang ZZ, Song ZX, 2021, Clinical Efficacy and Safety of Transcatheter Hepatic Artery Chemoembolization Intervention with Arsenic Trioxide in the Treatment of Middle and Advanced Primary Hepatocellular Carcinoma. Journal of Clinical and Experimental Medicine, 20(07): 705–708.

Hu ZM, Chen B, Zhong JN, et al., 2019, Progress in the Application of Therapeutic Methods for Primary Hepatocellular Carcinoma. Shandong Medicine, 59(09): 106–110.

Wang CX, Qin XH, Liu TL, 2021, Study on the Effect of Quantitative Analysis of Energy Spectrum CT on the Differential Diagnosis of Patients with Primary Liver Cancer and Liver Abscess. Journal of Medicine Forum, 42(13): 48–50.

Liu H, Yang JH, Wu MC, 2019, Current Status of Treatment of Postoperative Lung Metastasis from Primary Hepatocellular Carcinoma. Chinese Journal of Metastatic Tumors, 2019(04): 1–4.

Song LW, 2020, Current Status and Progress of Interventional Therapy for Patients with Primary Liver Cancer. Medical Equipment, 33(04): 201–202.

Yang YB, 2020, Effect of Transcatheter Hepatic Artery Embolization and Hepatic Artery Perfusion Chemoembolization in the Interventional Treatment of Primary Hepatocellular Carcinoma. Electronic Journal of Clinical Medicine Literature, 7(06): 48.

Li SJ, Xie QY, Xu SC, 2021, Clinical Efficacy of Transcatheter Arterial Infusion of Bevacizumab Combined with TACE for Primary Hepatocellular Carcinoma. China Prescription Drugs, 19(09): 117–118.

Wu ZL, Liu YZ, Li ZG, et al., 2018, Application Value of Precise Transcatheter Hepatic Artery Perfusion Chemoembolization in Elderly Primary Hepatocellular Carcinoma. Chinese Journal of Gerontology, 38(04): 857–859.

Shen YZ, Bai Y, Lu CY, et al., 2018, Study on the Recent Efficacy of Hepatic Artery Thermal Perfusion Chemoembolization Combined with Radiofrequency Ablation in the Treatment of Patients with Primary Hepatocellular Carcinoma. Journal of Practical Liver Disease, 21(03): 475–476.

Xie XW, Chen GB, 2021, He H, et al., 2021, Application Value of Cone-beam CT Technology in the Treatment of Primary Hepatocellular Carcinoma by Hepatic Artery Perfusion Chemoembolization. Journal of Hubei Medical College, 40(01): 51–55.

Gong Y, 2021, Observations on the Effect of Neutrophil-to-lymphocyte Ratio on the Prognosis of Patients with Primary Hepatocellular Carcinoma before Hepatic Artery Interventional Perfusion Chemotherapy/Embolization. Contemporary Medicine, 27(11): 39–41.

Wang L, 2021, Effects of Hepatic Artery Perfusion Chemoembolization on Survival Quality and Serum TNF-a, VEGF and bFGF Levels in Patients with Primary Hepatocellular Carcinoma Interventional Therapy. Electronic Journal of Modern Medicine and Health Research, 5(05): 17–20.

Zhang YF, Miao WY, Jing JY, 2022, Effect of Hepatic Artery Perfusion Chemoembolization on the Interventional Therapy of Primary Liver Cancer and its Influence on Patients’ Serum Indexes and Quality of Life. Journal of Medicine Forum, 43(09): 80–83.

Zhang W, Du HT, 2021, Comparison of the Effects of Transcatheter Hepatic Artery Embolization and Hepatic Artery Perfusion Chemoembolization in the Treatment of Primary Hepatocellular Carcinoma. Clinical Medicine, 41(03): 32–33.

Jiang YJ, Qiu D, Zheng P, et al., 2019, Comparison of Long-term Efficacy of Transcatheter Hepatic Artery Embolization and Hepatic Artery Perfusion Chemoembolization in the Interventional Treatment of Primary Hepatocellular Carcinoma. Electronic Journal of Clinical Medicine Literature, 6(23): 15–16.