Objective: To investigate the nursing effect of a modified intramuscular injection technique in the treatment of syphilis with benzathine penicillin. Methods: Eighty syphilis patients who underwent benzathine penicillin treatment at No. 2 People’s Hospital of Fuyang City from January 2019 to December 2022 were selected as research subjects. Following the principle of random grouping, they were divided into the experimental group (n = 40) and the control group (n = 40). Patients in the control group received conventional intramuscular injections of benzathine penicillin, while patients in the experimental group received intramuscular injections using a modified technique. The injection pain level, injection success rate, occurrence of local adverse reactions, and other indicators in both patient groups were observed. Results: The injection pain level in the experimental group was significantly lower than that in the control group (P < 0.05). Additionally, the injection success rate was significantly higher in the experimental group compared to the control group (P < 0.05). The incidence of local adverse reactions in the experimental group was significantly lower than that in the control group (P < 0.05). Conclusion: The improved intramuscular injection technique holds significant practical implications for enhancing the nursing effect of benzathine penicillin in syphilis treatment. It has the potential to improve the therapeutic outcomes of syphilis, enhance the quality of life for patients, and offer new ideas and methods for clinical nursing practices.
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