摘要
Objective: To analyze the effect of microwave combined with Sophora flavescens gel in patients with HPV infection and chronic cervicitis (CC). Methods: From May 2022 to May 2023, 65 patients with HPV infection complicated with CC were randomly selected and divided into group A (31 cases, microwave) and group B (34 cases, microwave + Sophora flavescens gel) by numerical numbering envelope method, and the effects of the two groups were compared. Results: The positive rate of vaginal microenvironment factors, inflammatory factor indexes, immune function indexes, and HPV-DNA viral load in group B were better than those in group A in the following month after treatment (P < 0.05). Conclusion: Combined use of microwave and Sophora flavescens gel in patients with HPV infection and CC can better improve the vaginal microenvironment and inflammatory reaction, boost the body’s immune function, and reduce HPV-DNA viral load.
参考
Deng L, 2021, Effect of Estrogen Ointment Combined with Radix Sophora Gel on Lactic Acid Bacteria Environment in Elderly Patients with Vaginitis. Contemporary Medicine, 27(8): 70–72.
Zhai M, Li H, 2023, Effect of Cryotherapy Combined with Interferon on Chronic Cervicitis Complicated with Human Papillomavirus Infection and its Influence on Photochemical Value/Critical Value Ratio and Inflammatory Cytokines. Maternal and Child Health Care of China, 38(13): 2354–2357.
Chen H, Xu J, 2022, Effect of Shugan Jianpi Jiedu Decoction Combined with Acupoint Application on Chronic Cervicitis Combined with HPV Infection and Its Influence on Immune Function. World Journal of Integrated Traditional and Western Medicine, 17(8): 1574–1579.
Chen H, Xu J, 2021, Recombinant Human Interferon ?: The Effect of 2a Suppository Combined with Laser Therapy on HPV DNA Load, Serum Hypersensitive C-Reactive Protein Levels, and Recurrence Rate in Patients with Chronic Cervicitis Complicated with HPV Infection. Maternal and Child Health Care of China, 36(18): 4375–4378.
He Q, Liu D, 2021, Clinical Effect of Recombinant Human Interferon ?2b Vaginal Effervescent Tablets Combined with Anti-Gongyan Tablets in the Treatment of Chronic Cervicitis Complicated with Human Papillomavirus Infection. Guangxi Medical Journal, 43(10): 1201–1204.
Dou L, Liu F, Miao R, 2021, Effect of Recombinant Human Interferon ?-2b on Inflammatory Factors and T Cell Subsets in Patients with Human Papillomavirus Infection Complicated with Refractory Cervicitis. Shanxi Medical Journal, 50(19): 2790–2792.
Ji H, Zhang H, Li L, et al., 2022, Clinical Study on Jiawei Xiaoduyin Combined with Interferon in Treating Persistent High-Risk Human Papillomavirus Infection in Cervical Region. Journal of Lanzhou University (Medical sciences), 48(4): 45–49 + 55.
Zhang C, Zhao F, Lu Q, et al., 2022, Effect of Qingre Tongli Decoction Combined with Acupuncture on Senile Chronic Cervicitis with HPV Infection. Chinese Journal of Gerontology, 42(17): 4229–4232.
Wang L, Liu N, 2023, Clinical effect of Microwave Combined with Interferon on HPV Infection Complicated with Chronic Cervicitis and its Influence on Vaginal Microecology. Journal of Clinical Research, 40(1): 130–133.
Hong L, Hu L, 2023, Clinical Effect of Sophora Gel Combined with Low-Dose Metronidazole on Trichomonal Vaginitis and its Influence on Inflammatory Factors. Heilongjiang Medicine Journal, 36(2): 384–387.