Keywords
Menotrophin
Polycystic ovary syndrome
Infertility
Submitted : 2024-06-24
Accepted : 2024-07-09
Published : 2024-07-24
Abstract
Objective: To investigate the clinical effects of Letrozole tablets combined with Menotrophin in infertile patients with polycystic ovary syndrome (PCOS). Methods: The time period of the study was from February 2023 to February 2024; 62 cases of PCOS infertility patients admitted to our hospital were selected and divided into an observation group (n = 31) and a control group (n = 31) by using the method of a random drawing of medical record number. The patients in the control group were treated with Letrozole tablets, and the patients in the observation group were treated with Letrozole tablets combined with Menotrophin, and the sex hormone levels, ovulation rate, the number of mature follicles, endometrial thickness, pregnancy rate, and early miscarriage rate were compared between the two groups. Results: Before treatment, the sex hormone levels of the two groups were compared, and there was no statistical difference (P > 0.05). After treatment, the sex hormone levels of the observation group were all better than those of the control group, and the differences were statistically significant (P < 0.05). The ovulation rate of the observation group was higher than that of the observation group, the number of mature follicles was more than that of the control group, and the endometrial thickness was greater than that of the control group, with statistically significant differences (P < 0.05). The pregnancy rate of the observation group was higher than that of the control group, and the rate of preterm delivery was lower than that of the control group, and the difference was statistically significant (P < 0.05). Conclusion: The combined application of Letrozole tablets and Menotrophin can improve the sex hormone level of PCOS infertility patients, promote their ovulation, improve follicular development, restore the thickness of endometrial lining, and increase the pregnancy rate of the patients and reduce the rate of preterm delivery, which is of value for promotion and application.
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