The Effect of Hysteroscopy Combined with Diane-35 on Endometrial Polyps and Its Impact on the Recurrence Rate

Abstract

Objective: To analyze the effect of hysteroscopy combined with Diane-35 on endometrial polyps and observe its value in reducing the recurrence rate. Methods: Between June 2022 and January 2023, 90 patients with uterine polyps who met the research criteria were included in the study. A controlled experimental design was employed, and the digital table random grouping method was utilized to divide the patients into the observation and control groups, with 45 cases in each. Patients in the control group underwent hysteroscopic polypectomy, diagnostic curettage during the operation, and routine anti-inflammatory treatment post-surgery. The observation group received Diane-35 treatment after hysteroscopy. The analysis included patient treatment effects, recurrence rate post-surgery, and endometrial thickness. Results: The effective rate among patients treated with combined Diane-35 was 95.56%, which was significantly higher than that among patients treated with hysteroscopy alone (82.22%; χ² = 4.050, P < 0.05). Both groups were followed up for one year. The recurrence rate in the observation group was 2.22%, significantly lower than that in the control group (13.33%; χ² = 3.873, P < 0.05). Preoperative endometrial thickness was compared between the two groups, showing no significant difference in the data (P > 0.05). However, at the 6-month and 12-month follow-up post-surgery, the endometrial thickness in the observation group was significantly lower than that in the control group (P < 0.05). After surgery, no adverse reactions such as uterine adhesion, infection, or massive bleeding occurred in either group (P > 0.05). Conclusion: Hysteroscopic surgery combined with Diane-35 yields higher efficacy in patients with endometrial polyps. This approach not only improves surgical outcomes but also reduces the recurrence rate of postoperative polyps and enhances the patient’s endometrial thickness, thus safeguarding the health of female patients.