The Clinical Anesthesia Effect of Remifentanil Combined with Propofol in Laparoscopic Cholecystectomy in the Elderly
Download PDF

Keywords

Diagnosis and treatment methods
Thyroidectomy
Remifentanil
Propofol
Complications

DOI

10.26689/aogr.v1i2.5293

Submitted : 2023-08-27
Accepted : 2023-09-11
Published : 2023-09-26

Abstract

Objective: To explore and analyze the effect of remifentanil combined with propofol for anesthesia in patients undergoing laparoscopic cholecystectomy, and to explore its clinical application value. Methods: A total of 64 patients who underwent laparoscopic cholecystectomy were selected and randomly divided into two groups, with 32 patients in each group. The anesthesia used in the control group was propofol combined with fentanyl, whereas the observation group was propofol combined with remifentanil and fentanyl. Medical staff routinely performed thyroidectomy on the patients after receiving anesthesia. After the treatment was completed, the researchers recorded the adverse reactions of the patients and the anesthesia effect during laparoscopic cholecystectomy and analyzed the anesthesia effect of the patients. Results: After the operation, the excellent and good rates of anesthesia in the observation group were significantly higher (P < 0.05). Pain in the observation group was significantly lower (P < 0.05). The clinical indicators after receiving anesthesia were significantly better in the observation group (P < 0.05). During the operation period, the two groups had different degrees of adverse reactions, while the incidence of adverse reactions in the observation group was relatively lower (P < 0.05). Conclusion: Patients in the observation group showed better anesthesia and lower pain levels during surgery, higher excellent and good rates of anesthesia, lower VAS scores, and better anesthesia indicators. Therefore, remifentanil-propofol combined anesthesia can be used as an effective anesthesia option in laparoscopic cholecystectomy, which improves the anesthesia effect during the operation and the postoperative pain control of patients and has clinical application value.

References

Chen X, He C, 2020, Study on the Analgesic Effect of Dexmedetomidine Combined with Propofol Anesthesia on Patients Undergoing Laparoscopic Cholecystectomy. Journal of Practical Hepatology, 23(3): 443–446.

Chen R, Shen X, Ni H, et al., 2018, Comparison of the Effects of Sufentanil and Remifentanil Combined with Propofol Intravenous Anesthesia in Laparoscopic Cholecystectomy. Chinese Journal of General Surgery, 27(8): 1041–1047.

Chen Y, Xu L, Lan Z, et al., 2017, Effects of Sevoflurane, Propofol Combined with Dexmedetomidine on Postoperative Cognitive Function and Oxidative Stress in Patients Undergoing Laparoscopic Cholecystectomy. Chinese General Medicine, 15(8): 1283–1285.

Wang K, Fu S, 2017, Study on the Anesthesia Effect of Sufentanil Combined with Propofol Intravenous Anesthesia in Laparoscopic Cholecystectomy. Drug Evaluation Research, 40(2): 252–254.

Li X, Zhu M, 2016, Effects of Propofol and Remifentanil Combined Intravenous Anesthesia on Postoperative Cognitive Function in Elderly Patients Undergoing Laparoscopic Cholecystectomy. Medical Review, 22(10): 1970–1973.

Zhu Y, Wu J, Wang M, 2016, Comparison of the Application Effect of Total Intravenous Anesthesia with Sufentanil and Remifentanil Combined with Propofol in Laparoscopic Cholecystectomy. Clinical Rational Drug Use, 9(3): 54–55.

Jiang Y, Zhao S, 2016, Effects of Remifentanil Combined with Propofol Anesthesia on Stress Response and Blood Gas Indexes in Patients Undergoing Laparoscopic Cholecystectomy. Journal of Hainan Medical College, 22(7): 677–679 + 682.

Ma Y, Li Q, Liu J, 2015, Anesthesia Effect Analysis of Remifentanil Combined with Propofol for Laparoscopic Cholecystectomy. Medical Review, 21(18): 3449–3451.

Bian B, Xue R, Guo Y, et al., 2015, Effects of Etomidate and Propofol on Cognitive Dysfunction in Elderly Patients After Laparoscopic Cholecystectomy. China Pharmacy, 26(23): 3244–3246.

Liu N, 2015, Effect of Sevoflurane Combined with Propofol Intravenous Anesthesia on Early Cognitive Function in Elderly Patients After Laparoscopic Cholecystectomy. Chinese Journal of Clinicians, 43(2): 69–72.

Lu Z, Yan D, 2015, Effects of Propofol and Remifentanil Combined Intravenous Anesthesia on Postoperative Cognitive Function in Elderly Patients Undergoing Laparoscopic Cholecystectomy. Chinese Journal of Gerontology, 35(2): 289–291.

Li D, Zeng Q, Liang H, et al., 2014, Effect of Remifentanil Combined with Propofol Anesthesia on Hemodynamics in Laparoscopic Cholecystectomy. Medical Review, 20(14): 2666–2668.

He Y, Ye X, 2014, Effects of Propofol and Remifentanil Combined Intravenous Anesthesia on Cognitive Function After Laparoscopic Cholecystectomy. Zhejiang Trauma Surgery, 19(1): 135–137.

Wang X, Ye W, Yi Y, 2013, Anesthesia Effect of Remifentanil Combined with Propofol for Laparoscopic Cholecystectomy. Journal of Hunan University of Traditional Chinese Medicine, 33(8): 43–44.

Feng L, Zhang S, Xia P, et al., 2010, Comparison of Anesthesia Effects of Sevoflurane or Propofol Combined with Remifentanil in Elderly Laparoscopic Cholecystectomy. Journal of Practical Medicine, 26(1): 118–120.