Objective: To explore the seasonal changes of hemorheology in patients with intracerebral hemorrhage in acute phase. Methods: The hemorheology indexes were detected in 100 acute cerebral hemorrhage patients and 30 normal persons. The observed group were divided into summer group, transition season group and winter group according to traditional solar terms, then the hemorheology indexes of different groups were compared. Results: Compared with control group, the whole blood viscosity increased with statistical significance(P<0.05). The whole blood viscosity of four cut blood rates and plasma viscosity were further compared in summer group, transition season group and winter group, and the indexes were the highest in winter group. Compared with transition season group, the erythrocyte aggregation index and erythrocyte transformation index acute intracerebral hemorrhage patients were decreased in winter group and summer group. The whole blood viscosity, plasma viscosity and erythrocyte sedimentation rate(ESR) compared in each group were increased with statistical significance. There were no significant statistical differences in hematocrit(HCT) among each groups(P>0.05). Conclusion: The hemorheology indexes in acute intracerebral hemorrhage patients are influenced by changes of different seasons and The blood of acute cerebral hemorrhage patients shows a concentrated tendency. The whole blood viscosity and plasma viscosity of acute cerebral hemorrhage patients were increased more obviously in winter group, which may be a pathophysiological basis of high incidence of acute cerebral hemorrhage in cold season and increase of severe cases.