ã€Abstractã€‘Objective: To investigate the clinical efficacy of carboprost tromethamine combined with mifepristone in the treatment of uterine fibroids. METHODS: A total of 66 patients with uterine fibroids admitted to our hospital between April 2018 and January 2019 were selected as subjects. According to the two different treatment methods, patients were divided equally. The observation group and the control group, each group of 33 people. The oxytocin drug treatment was medicated to the control group, and the prostaglandin tromethamine combined with mifepristone was medicated to the observation group. The treatment effect, adverse reaction, operation, and uterine muscle before and after surgery were observed in these two groups. Tumor tissue progesterone receptor and estrogen receptor levels. Results: The clinical treatment effect of the observation group was 93.94%, and the clinical treatment effect of the control group was 60.61%. The clinical treatment effect of the observation group was significantly higher than that of the control group; also the incidence of adverse reactions in the observation group in terms of rash, fatigue, nausea and vomiting was much lower than the control group, and could observe a significant difference. Finally in observation group, the amount of intraoperative blood loss, operation time and hospitalization time were better than those of the control group. The progesterone receptor and estrogen receptor levels in the uterine fibroid tissue after surgery should also be better than the control group, it is worth to make further comparison. Conclusion: Carprostol tromethamine combined with mifepristone is effective in the treatment of uterine fibroids and can be further developed.
Yu Shi. Therapeutic effect of carboprost tromethamine combined with mifepristone on uterine fibroids[J]. China continuing medical education, 2018, 10 (23): 111-113.
Shuhua Li. Therapeutic effect of kaempferol tromethamine combined with mifepristone on uterine myomectomy[J]. Medical Theory and Practice, 2018, 31(19): 2931-2932.
Feng Dong, Xueling Lou, Zhanxin Zhang, et al. Application of carprostol tromethamine injection in uterine fibroids removal[J]. Journal of North Pharmacy,2018,15(10):72 -73.
Xiaomin Chen, Yan Jing, Lixuan Guo. Clinical study of kaempeatin tromethamine in uterine fibroids removal during cesarean section[J]. International Medicine & Health Guidance, 2018, 24(15): 2258-2260 , 2264.
Qinghong Zheng. Clinical application of carprostol tromethamine in uterine fibroids removal during cesarean section [J]. Special Health, 2018 (16): 97.
Xueling Lou, Li Yao, Zhanxin Zhang, et al. Clinical observation of the application of carboprost tromethamine injection in uterine myometrial fibroids removal surgery [J]. Chinese folk therapy, 2018, 26 (11): 90-92.
Lixuan Guo, Xiaomin Chen, Yan Jing. Comparison of the value of carprostol tromethamine and oxytocin in uterine fibroids removal during cesarean section[J]. Chinese Medical Sciences Journal,2018,8(14): 91-93.
Congzhe Wu, Yingxin Zhang, Xin Zhao, et al. Study on hemostasis effect of different administration methods of laparoscopic hysteromyoma removal with carboprost tromethamine[J]. China Comprehensive Clinical, 2017, 33(10): 882 -886.