Effect of Ketoprofenphonophoresis and Femoral Nerve Block in Knee Osteoarthritis
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Keywords

Ketoprofenphonophoresis
Femoral nerve block
Knee osteoarthritis

DOI

10.26689/jcnr.v5i6.2710

Abstract

Objective: To evaluate the effect of ketoprofenphonophoresis and femoral nerve block in knee osteoarthritis. Methods: One hundred and fourteen patients with knee osteoarthritis were randomly divided into two groups. The control group consisted of 57 patients who were treated with only ketoprofenphonophoresis. The experimental group consisted of patients were treated with ketoprofenphonophoresis and femoral nerve block. The patients were followed for more than one month. The treatment effect assessed by observing their WOMAC index before and after therapy. Results: All the patients finished the follow-up. Their WOMAC indexes were reduced after therapy and one month after treatment, especially in the experimental group (P < 0.05). The effective efficiency of ketoprofenphonophoresis and femoral nerve block were higher than that in the control group after treatment and after one month of follow-up (P < 0.05). Conclusion: Compared with only ketoprofenphonophoresis, the combined treatment of ketoprofenphonophoresis and femoral nerve block was more appropriate in knee osteoarthritis.

References

Tang X, Wang SF, Zhan SY, et al., 2016, The Prevalence of Symptomatic Knee Osteoarthritis in China Results from the China Health and Retirement Longitudinal Study. Arthritis Rheumatol, 68(3): 648-653.

Joint Surgery Group, 2019, Orthopaedic Branch, Chinese Medical Association Expert Consensus on Step Therapy for Knee Osteoarthritis (2018 Edition). Chinese Journal of Joint Surgery (Electronic Edition), 13(1): 124-130.

Wu H, Deng HW, Liu LP, et al., 2012, Clinical Study of Focused Ultrasound in Treatment of Knee Osteoarthritis. Chinese Journal of Postgraduates of Medicine, 35(8): 39-41.

Zhang LN, 2016, Clinical Observation of Ultrasound-guided Femoral Nerve Block. China Practical Medicine, 11(24): 22-23.

Chinese Medical Association, 2013, Clinical Technical Operation Specification: Pain Volume.People’s Military Medical Press, Beijing, 78-87.

Chinese Medical Association, 2007, Clinical Diagnosis and Treatment Guidelines: Pain volume, People’s Medical Publishing House, Beijing, 14-15.

Vos T, Flaxman AD, Naghavi M, et al., 2012, Years Lived with Disability (YLDs) for 1160 Sequelae of 289 Diseases and Injuries 1990-2010: A Systematic Analysis for the Global Burden of Disease Study 2010. Lancet, 380(9859): 63-96.

Wu ZJ, 2018, Etiology, Pathogenesis and Treatment Progress of Knee Osteoarthritis. Chinese Journal of Medical Device, 31(4): 203-204.

Khan M, Adili A, Winemaker M, et al., 2018, Management of Osteoarthritis of the Knee in Patients. CMAJ, 190(3): E72-E79.

Zheng XF, 2017, Pathogenesis and Recent Advances in Treatment of Osteoarthritis. Chinese Journal of Tissue Engineering Research, 21(20): 3255-3262.

Li WP, Jian R, Xu FY, 2012, Effect of Ultrasonic Treatment on the Expression of MMP-1 and MMP-13 in Rabbit Knee Osteoarthritis. Chongqing Medical, 41(16): 1564-1566.

Wu Y, Zhu S, Lv Z, et al., 2019, Effects of Therapeutic Ultrasound for Knee Osteoarthritis: A Systematic Review and Meta-Analysis. SAGE Journals, 33(12):1863-1875.

Jain M, Srivastava V, Kumar R, et al., 2017, Determination of Five Potential Genotoxic Impurities in Dalfampridine Using Liquid Chromatography. J Pharm Biomed Anal, 133(3): 27-31.

Guan S, Duan XQ, Qiao SX, et al., 2010, Clinical Observation of Ketoprofenphonophoresis In the Treatment of Senile Knee Osteoarthritis. Chinese Journal of Gerontology, 3(30): 582-583.

Wang YD, 2018, Effect of Ultrasound Combined with Sodium Hyaluronate on Knee Function in Patients with Knee Osteoarthritis. Journal of Frontier of Medicine, 8(28): 122-123.

Fan GM, Gong SL, Dai JP, et al., 2012, Effect of Femoral Nerve Block on Serum Substance P Content in Rabbits with Osteoarthritis. Chinese Journal of Pain Medicine, 18(4): 238-241.

Wang DS, Wang L, Chen Q, et al., 2010, Effect of Lumbosacral Plexus and Branch Nerve Block on Cytokine Content in Articular Fluid of Knee Osteoarthritis. Chinese Journal of Painology, 6(41): 266-268.

Lei L, Wang L, Wei W, 2017, Comparative Study of Two Nerve Block Therapies in the Treatment of Knee Osteoarthritis. Chinese Journal of Pain Medicine, 23(4): 307-309.

Bannuru RR, Osani MC, Vaysbrot EE, et al., 2019, OARSI Guidelines for the Non-Surgical Management of Knee, Hip, and Polyarticularosteoarthritis. Osteoarthritis and Cartilage, 6(11): 1-35.