Objective: To explore the clinical value of carotid artery stent implantation (CAS) and carotid endarterectomy (CEA) in the treatment of patients with severe internal carotid artery stenosis. Methods: 88 patients with severe carotid artery stenosis who underwent CAS and CEA in the First People’s Hospital of Changde City (hereafter referred as “our hospital”) from January 2018 to December 2020 were selected as the research objects and divided into CAS group (n = 43) and CEA group (n = 45). To understand the clinical application value and feasibility of the two surgical schemes by comparing the general situation, cerebral blood flow, MMSE scale, MOCA scale score and serum miR-145, IGF1R levels of the two surgical schemes. Conclusions: CAS and CEA in the treatment of patients with severe internal carotid artery stenosis, have good curative effect, can effectively improve the patient's cerebral blood flow, regulate serum miR-145, IGF1R levels, promote the recovery of cognitive function, but relatively speaking, the incidence of stroke and hypotension after CAS is higher, and the incidence of hypertension after CEA is higher.
Wang D, Liang W, Gao Y, 2021, Observation on the Effect of Stent Placement After Small Balloon Dilatation in the Treatment of Severe Stenosis at the Beginning of Internal Carotid Artery. Chinese Journal of Practical Medicine, (06):10.
Hu C, Dong R, Shi F, et al., 2021, Effect of CAS and CEA On Cerebral Blood Flow, Serum miR- 145 and IGF1R in the Treatment of Severe Internal Carotid Artery Stenosis. Progress of Modern Biomedicine. (03) - 30
Liu Q, Yu C, Jia H, et al., 2021, Effect of Internal Carotid Artery Stenting on Cognitive Impairment in Patients with Severe Internal Carotid Artery Stenosis and Analysis of Related Risk Factors. Chinese Journal of Physicians, 1:20.
Chen C, Yuan X, Han J, et al., 2020, Efficacy and Safety of Staged Stenting in the Treatment of Subtotal Occlusion of Internal Carotid Artery with Contralateral Internal Carotid Artery Stenosis. Chinese Journal of Stroke, (08):20.
Sun Q, Mao M, Yan W, et al., 2020, Effect of Carotid Artery Stenting on Cognitive Function of Patients with Severe Internal Carotid Artery Stenosis. Contemporary Medicine, (07):25.
Yuan H, Qian K, Fu F, et al., 2020, Analysis of Early Curative Effect of Modified Carotid Endarterectomy for Severe Carotid Stenosis. Chinese Journal of Vascular Surgery (Electronic Edition), (06):20.