Analysis of Clinical Symptoms Improvement in Treatment of Severe Pneumonia Caused by Multi-drug Resistant Bacterial Infection by Bronchoscopy Alveolar Lavage
PDF

Keywords

Bronchoscopy alveolar lavage
Multi-drug resistant bacteria
Severe pneumonia
Clinical symptoms

DOI

10.26689/jcnr.v5i4.2301

Abstract

Objective: To explore the effects of bronchoscopy alveolar lavage in the treatment of severe pneumonia caused by multiple drug bacterial infection. Methods: A total of 84 patients with severe pneumonia infected by multi-drug resistant bacteria were randomly selected from Kunming Second People’s Hospital, which is our hospital from January 2019 to December 2020 for this research. They were divided into a reference group and a study group using a digital table method, with 42 cases in each group. The reference group was given the routine treatment, the research group performed bronchoscopy alveolar lavage on this basis to observe the curative effect. Results: Before treatment, there was no significant difference in serum factor indexes and blood gas analysis indexes between the two groups of patients, P>0.05. After treatment, the time of fever, cough, moist rales disappearing and infection control time in the study group were shorter than those in the reference group, P<0.05. Serum tumor necrosis factor ? (TNF-??), interleukin-6 (IL-6) and interleukin-8 (IL-8) levels were lower than the reference group, and the arterial partial pressure of oxygen (PO2) and oxygen saturation (SO2) were both lower than the reference group, P<0.05. The effective rate of the treatment in the study group was higher than that in the reference group, P<0.05. Conclusion: Bronchoscopic alveolar lavage treatment can effectively improve the clinical symptoms of patients with severe pneumonia caused by multi-drug resistant bacterial infection, and the effects are significant.

References

Luo WJ, Wang CM, Hu YF, et al., 2019, Analysis of the Efficacy of Bronchoalveolar Lavage Tanreqing Injection in the Treatment of Multidrug-Resistant Acinetobacter Baumannii Pneumonia in Critically Ill Patients. Chinese Medicine Guide.

Wang Y, 2019, Clinical Analysis of Electronic Bronchoscope Alveolar Lavage in the Treatment of Severe Pulmonary Infection. Digest of World Latest Medical Information (Electronic Edition), 019(077):101-102.

Pang HB, 2020, The Clinical Effect of Bronchoscopy Lavage Combined with Antibiotics in the Treatment of Refractory Pulmonary Multidrug-Resistant Bacteria Infection. Journal of Practical Clinical Medicine, 024(003): 19-21.

Jun XU, Hui LI, Wen L, et al., 2019, Clinical Effect of Fiberoptic Bronchoscopic Sputum Aspiration and Bronchoalveolar Lavage in the Treatment of Pulmonary Infection in Respiratory Intensive Care Unit.

Fang F, Wang YT, Bi LX, et al., 2020, The Etiological Characteristics of Severe Pneumonia in Children with Respiratory Failure and Analysis of the Therapeutic Effect of Bronchoscopy Alveolar Lavage. Chinese Journal of Nosocomial Infection, 30(08): 165-170.

Gao YW, Song JG, Wang DM, 2020, Efficacy and Mechanism Analysis of Electronic Bronchoscope Alveolar Lavage on Children with Severe Pneumonia. Guizhou Medicine, 44(10):43-44.

Zhang J, 2020, Analysis of the Effect of Bronchoscopy Alveolar Lavage Combined with Ambroxol Hydrochloride in the Treatment of Severe Pneumonia in Children. China Journal of Modern Medicine, (1):64-66. volume

Lei LL, Han ZY, Wang Y, 2019, Analysis of the Efficacy of Bronchoalveolar Lavage in the Treatment of Patients with Ventilator-Associated Pneumonia. Internal Medicine, 014(003): 300-302,341.