Objective: This paper mainly explores the application value of unprotected midwifery care for primipara natural childbirth. Methods: 120 primiparas in our hospital from January 2017 to February 2019 were divided into routine group and Research Group, 60 cases in each group. The routine group was given routine perineal protection midwifery, and the Research Group was given routine midwifery nursing. The nursing intervention effects of the two groups were compared statistically. Results: After statistics, VAS score and bleeding volume of perineal pain in the Research Group were lower than those in the conventional group, and the length of hospital stay in the Research Group was less than that in the conventional group, P< 0.05; There was no significant difference in the time of the first stage of labor, the second stage of labor and the third stage of labor between the Research Group and the conventional group (P> 0.05); The incidence of complications in the Research Group was lower than that in the conventional group (P< 0.05).Conclusion: The application value of unprotected midwifery nursing intervention in primipara natural childbirth is significant.