Abstract: Objective: To investigate the clinical effects of electroacupuncture combined with extracorporeal shock wave in the treatment of periarthritis of shoulder. Methods: 136 patients with periarthritis of shoulder admitted to our hospital from September 2018 to September 2019 were randomly divided into two groups by double-blind method. 68 patients in the control group were treated with extracorporeal shock wave; 68 patients in the observation group were treated with electroacupuncture combined with extracorporeal shock wave. The shoulder joint pain, joint function and activities of daily living were compared between the two groups. Results: The VAS score of shoulder joint pain in the observation group after treatment (1.92±0.24) was lower than that in the control group (3.51±0.32), and the UCLA score of shoulder joint function (31.28±1.96) was higher than that of the control group (27.42±2.36), the differences were statistically significant (P<0.05). After treatment, the active degree of forward flexion and extension of shoulder joint in the observation group was higher than those of the control group, and the activities of daily living was higher than that of the control group, with statistically significant differences (P<0.05) Conclusion: Electroacupuncture combined with extracorporeal shock wave treatment for periarthritis of shoulder has achieved ideal effects, safety and non-invasiveness, and can quickly restore the functions of shoulder joints.